The impact of hormonal treatment on the development of the hip in multiple pregnancy – sonographic assessment
Journal Title: Postępy Nauk Medycznych - Year 2012, Vol 25, Issue 6
Abstract
<b>Introduction.</b> An increasing number of multiple pregnancies have been observed within the last twenty years. Multiple pregnancies occur more often in families that have had twins before, or have undergone infertility treatment with hormonal agents to stimulate ovulation. The etiology of DDH – developmental hip dysplasia is multifactorial and is influenced by genetic, hormonal and mechanical factors. Many DDH risk factors occur with greater frequency in multiple pregnancies. The aim of this prospective study was to evaluate the influence of hormonal (gonadotropins, progestogens) treatment on DDH incidence in twins and other multiples.<br><b>Material and methods.</b> 400 hip joints of 200 newborns were examined ultrasonographically with Graf method. Our sample consists of 166 hip joints of 83 multiples whose mothers had undergone hormonal treatment (Group A) and 234 hip joints of 117 multiples whose mothers had not undergone hormonal treatment (Group B).<br><b>Results.</b> Group A had 8 Graf Type IIa 8 hips (4.85%), 104 Graf Type Ia hips and 54 Graf Type Ib hips. Group B had 20 Graf Type IIa hips (8.51%), 165 Type Ia hips and 49 Graf Type Ib hips. The incidence of Graf Type IIa was higher in Group B. The difference was statistically significant (p < 0.05).<br><b>Conclusions.</b> Hormonal treatment in a multiple pregnancy cannot be regarded as a risk factor for increased incidence of Graf Type IIa hips.
Authors and Affiliations
Andrzej Sionek, Jarosław Czubak, Maria Kornacka, Bartłomiej Grabowski
Keywords
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