The Impact of Peripheral Enhancement in Magnetic Resonance Imaging on the Treatment Outcomes of Patients with Glioblastoma Multiform
Journal Title: International Journal of Health Sciences and Research - Year 2017, Vol 7, Issue 9
Abstract
Background: This study was done in clinical oncology and radio-diagnosis departments of Assiut University Hospital during a period of two years and involved patients' records presented to clinical oncology department from January 2013 to December of 2014. Patients and methods: Only 25 cases with glioblastoma multiform (GBM) were eligible to be included in this retrospective study. Results: 22 patients showed variable percentages of peripheral enhancement (PE) with a mean value of 62.8%. Decreased percentage of PE was associated with better response to standard treatment (P=0.001). The median progression free survival (PFS) and overall survival (OS) were 12 ± 1.2 months and 13±1.499 months respectively, PE was negatively correlated with survival (PFS and OS) with significant effect (P=0.03 and 0.000 respectively). Conclusion: the percentage of PE had a significant prognostic impact on response and survival of GBM, but still the study needed to be evaluated in larger cohort studies to determine the accurate prognostic role of PE in GBM.
Authors and Affiliations
Amal Rayan
Keywords
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