The implementation of randomized trials in the treatment of advanced ovarian cancer with HIPEC: waiting for new evidence

Journal Title: Journal of Cancer Research & Therapy - Year 2013, Vol 1, Issue 1

Abstract

Ovarian cancer (OC) is one of the most frequent mortality causes among female neoplasms. A lot of data is available on the efficiency and the relative safety of the different treatments. In the last twenty years the overall survival (OS) and the disease free survival (DFS) have enormously incremented thanks to the combined chemotherapy regimens and the incredible progresses of surgery. These progresses are also related to the increased ability in managing patients more and more compromised, i.e. older and weaker. In addition to that, more than twenty years ago, Sugarbaker et al. started to treat the peritoneal cancer diffusion as a loco-regional disease. This change of practice has been demonstrated to be a real revolution by following studies.

Authors and Affiliations

Coccolini F, Lotti M, Catena F, Pisano M, Grosso G, Frigerio L, Ansaloni L

Keywords

Related Articles

Predictive and prognostic value of classification by immunohistochemical phenotypes in localised breast cancer treated with dose-dense adriamycin/cyclophosphamide

Introduction: Histopathologic subtyping according to the St. Gallen classification is predictive of response in women with breast cancer treated with neoadjuvant chemotherapy (NCT). Our aim was to confirm its predictive...

Body composition, somatotype and risk of premenopausal breast cancer: a case-control study in Uruguay

In order to analyze detailed anthropometric characterisation for risk of breast cancer (BC) in premenopausal Uruguayan women, a case-control study was carried out at the Pereira Rossell Women’s Hospital, Montevideo, wher...

KRAS testing and first-line treatment among patients diagnosed with metastatic colorectal cancer using population data from ten National Program of Cancer Registries in the United States

Background: In 2011, the National Comprehensive Cancer Network (NCCN) recommended KRAS testing for metastatic colorectal cancer (mCRC) patients. Our study assessed KRAS testing prevalence and its association with socio-d...

Malignant solitary fibrous tumor of the sacrum: A case report

The solitary fibrous tumor (SFT) is a rare ubiquitous mesenchymal neoplasm of fibroblastic type, which shows a prominent hemangiopericytoma-like branching vascular pattern. Approximately 40% of solitary fibrous tumors ar...

Factors associated with refusal of radiotherapy among oral cancer patients

Background: Surgery is commonly favored in the management of oral cancer but radiotherapy may be essential because of the size or location of the tumor. Refusal of radiotherapy by patients is an important issue, which mu...

Download PDF file
  • EP ID EP550159
  • DOI 10.14312/2052-4994.2013-9
  • Views 79
  • Downloads 0

How To Cite

Coccolini F, Lotti M, Catena F, Pisano M, Grosso G, Frigerio L, Ansaloni L (2013). The implementation of randomized trials in the treatment of advanced ovarian cancer with HIPEC: waiting for new evidence. Journal of Cancer Research & Therapy, 1(1), 60-61. https://europub.co.uk/articles/-A-550159