The importance of branched chain amino acids in human nutrition and prevention, and the course of certain diseases
Journal Title: Medycyna Ogólna i Nauki o Zdrowiu - Year 2013, Vol 19, Issue 3
Abstract
Branched chain amino acids (leucine, isoleucine, valine) are mainly constituents of proteins, but also regulate many physiological processes in the human body. The aim of this study was to analyze the current state of knowledge about the importance of BCAA in human beings, their use in the nutrition of the healthy and sick, and in the prevention of some diseases. Adult needs for leucine, valine and isoleucine are, respectively: 40, 17–25, 19 mg / kg body weight. Deficiencies in the intake of BCAA’s are rare and concerns groups consuming inadequate amounts of protein in the diet, and those suffering from kidney and liver diseases in which protein metabolism is disturbed. The available data show that doses of two or even three times higher than those recommended are well tolerated and do not cause any side effects. A sufficiently high concentration of branched chain amino acids in the blood is a factor in the limited uptake of tryptophan, tyrosine and phenylalanine to the brain. This property is used in the treatment of several diseases, such as cirrhosis and hepatic encephalopathy, phenylketonuria, bipolar disorder, tardive dyskinesia and cachexia syndrome. Branched chain amino acids, in addition to their constituent function, also play a regulatory role in the effect on the secretion of hormones and catecholamines, the formation of neurotransmitters, and stimulation of protein synthesis. They can be a source of energy, influence wellbeing, reduce physical fatigue. They are a substrate for the synthesis of other amino acids and are an important factor in the treatment of certain diseases.Key words: branched chain amino acids, leucine, isoleucine, valine, demand
Authors and Affiliations
Małgorzata Ewa Drywień, Jakub Dźwigała, Marzanna Staszewska-Skurczyńska
Keywords
Related Articles
- EP ID EP69767
- DOI -
- Views 194
- Downloads 0
Gender as a factor differentiating conditions of functioning of the disabled in the rural environment of Lublin Region
As a result of the growth of women’s cultural capital during last ten years in Poland, meaningful changes have been observed in the area of performance of roles by females and males. It may be presumed that the differen...
Selected aspects of quality of life of patients with degenerative changes in the spine and joints
Introduction: The ageing of society is associated with an increase in the frequency of occurrence of many diseases typical of geriatric age, which hinder the functioning of many of the elderly and deteriorate the quality...
Overview of the female population, members of the Amazons Club and analysis of their work and financial situation before and after mastectomy
Introduction: In Poland and worldwide, breast cancer is the most common malignancy among women. Every 14 women will contract the disease in their lifetime. Women struggling with breast cancer are called the Amazons. The...
Fibrous-hyperplastic changes of oral cavity mucosa. Own observations
Fibrous-hyperplastic changes of the mucous membrane of the oral cavity, caused by using removable dentures, are often met in dental practice. In literature, they are well-known under the terrms: granulomas fissurati, and...
Evaluation of health promoting behaviours concerning breast cancer among women living in the Lublin Macroregion
Introduction: In our age, due to increasing social awareness, a higher level of knowledge, and progress in medicine, breast cancer is detected earlier, diagnosed, and treated. However, despite various prophylactic action...