The Incidence of Lesions of Different Systems and Organs in Children with Gastroesophageal Reflux Disease
Journal Title: Здоров`я дитини - Year 2016, Vol 6, Issue 74
Abstract
Introduction. Gastroesophageal reflux disease (GERD) — a chronic recurrent disease caused by the disturbances of the motor-evacuating function of the gastroesophageal zone and is characterized by spontaneous and/or regular reflux of the gastric or duodenal fluid that leads to the damage of the distal part of the esophagus. GERD is one of the most frequent diseases that affect the esophagus. Taking into the account the huge amount of the causes, which may lead to GERD, its etiology is still not well defined, and the contribution of each factor requires further analysis. The aim of the study was to analyze the peculiarities and the incidence of GERD association with other organ and system pathologies.Materials and methods. Clinical analysis of 73 cases of GERD in school-aged children has been performed. The incidence of GERD combination with other system and organ pathologies has been evaluated using thorough anamnesis and patient’s medical history analysis. Results. In 66 % of children with GERD, the association of this pathology with other digestive tract diseases has been revealed, in 50.7 % — with lesions of musculoskeletal system, in 12.3 % — with urinary tract pathology. Almost one third of children with GERD suffered from congenital defects of different organs and systems, such as dolichosigmoid, mitral valve prolapse, nephroptosis/rotation of the kidneys/pyelectasis/bladder-pelvic reflux, gallbladder deformities. The article presents the analysis of a clinical case of the combination of cardiovascular, digestive and urinary lesions that enables us to assume the presence of possible common etiology factor of the diagnosed diseases. The analyzed data regarding the association of GERD with other organ and system pathologies, as well as the results of other research groups indicate a probable common component in their etiology. The common factor in the described cases of the combination of pathologies may be a violation of the connective tissue synthesis/undifferentiated connective tissue dysplasia.
Authors and Affiliations
O. Z. Gnateyko, M. I. Dats-Opoka, O. L. Lychkovska, T. Yu. Tsyolko
Keywords
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- EP ID EP182902
- DOI 10.22141/2224-0551.6.74.2016.82140
- Views 98
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