The morpho-functional features of the left ventricular myocardium and common carotid arteries in children with cystic fibrosis
Journal Title: Здоров`я дитини - Year 2017, Vol 12, Issue 5
Abstract
Background. The features of the morpho-functional state of the left ventricular myocardium and common carotid arteries were studied according to echocardiography in children with cystic fibrosis. Materials and methods. 72 children with cystic fibrosis were examined. To determine the preclinical stage of left ventricular diastolic dysfunction, a functional compliance index (FCI) was determined by the method of A.N. Rosenbaum and V.T. Koval (2010). Results. The results of the study showed the development of left ventricular myocardium remodeling in 58 % of patients with cystic fibrosis, among the variants of which eccentric hypertrophy predominated. The revealed changes increased with an increase in the severity of the course of the disease. The analysis of diastolic function of the left ventricle by standard method in the group of patients with cystic fibrosis did not reveal any significant differences from the parameters of the control group. The FCI calculation showed that in 37.5 % of children with cystic fibrosis, which indicated the formation of left ventricular diastolic dysfunction, which progressed in the course of the disease, it decreased with respect to the values of the control group. The most pronounced changes in FCI were found with concentric left ventricular myocardial hypertrophy and with severe disease. Conclusions. The identified morpho-functional rearrangement of the left heart occurred against the background of remodeling and hemodynamic changes at the level of the common carotid artery in children with cystic fibrosis.
Authors and Affiliations
O. E. Pashkova
Keywords
Related Articles
- EP ID EP221454
- DOI 10.22141/2224-0551.12.5.2017.109270
- Views 94
- Downloads 0
Modern Methods of Mucoactive Therapy for Respiratory Diseases in Children
The article deals with the issues of rational and optimal mucolytic therapy for respiratory diseases in children. The approaches to the choice of therapy are considered based on the pathogenetic mechanisms of disorders o...
Features of Onset and Clinical Course of Reactive Arthritis in Children
Objective: to identify the characteristics of the onset and clinical course of reactive arthritis in children at the present stage. Material and methods. 81 children with reactive arthritis aged from 2 to 18 years have b...
The role of galectin-3 in the development of nephropathy
The purpose of this review was to analyse literature on the role of galectin-3 (Gal-3) in the development of nephropathy. We searched for published and unpublished data using Pubmed as the search engine by the keywords:...
Age-Associated Motor Disorders in Inflammatory Digestive Pathologies
As a result of the complex gastroduodenopolymetry with the ultrasonic monitoring of the gallbladder and pancreas in an interdigestive period in 30 healthy children and adolescents and 304 patients with the gastroduodenal...
Antibiotic therapy of community-acquired pneumonia in children: comparison of international guidelines and current practice in Ukraine
Background. Respiratory diseases are a serious medical and social problem in pediatrics. The aim of the study was to research the current scientific sources for the treatment of community-acquired pneumonia in children,...