The muscular effect of Cobra energy drink on toad (Bufo marinus = Rhinella marina) gastrocnemius fatigue time and contraction force
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 7
Abstract
Background: Cobra energy drink is one of the most popular beverages in the Philippines used by many for its energy-boosting effects. It is known to contain ingredients such as caffeine, B-vitamins, taurine, and ginseng, which are all said to improve muscle performance. Caffeine helps aid muscle contraction through the opening of calcium ion channels, while B vitamins aid in the production of adenosine triphosphate needed by the muscles during exercise. In addition to this, taurine helps maintain contractile functions while ginseng protects the muscles from exercise-induced oxidative stress. Aims and Objectives: The objectives of the study are to determine the effect of Cobra energy drink on the contraction force and fatigability of the gastrocnemius muscle of toad. Materials and Methods: Cobra energy drink was administered in four different concentrations (100% v/v, 75% v/v, 50% v/v, and 25% v/v). Each treatment concentration had four replicates each and a total of 16 toads were used. For each toad, both legs were used, one leg for the treatment and the other one for the control. The factors measured are as follows: Mean force, maximum force, and fatigue time. These parameters were measured using the PowerLab/4ST. Results: Based on the results gathered, 100% v/v showed an increase in muscle contractility by garnering a positive result for all three factors while the rest of the treatments gave negative means for all three factors. Means for 100% v/v were considered statistically significant from all the other treatments while the rest showed no significant differences. Moreover, no significant differences were detected from all treatments in fatigue time including the 100% v/v. However, the results imply that as the treatment concentration increased, muscle contractility also increased. 100% v/v showed the most promising results in muscle contraction and fatigability due to it gaining positive values for all three parameters while the other treatments gave negative results. Conclusion: It can be said that Cobra energy drink had a beneficial effect on the muscle in terms of muscle contractility due to the significant differences detected in muscle contractility and fatigability.
Authors and Affiliations
Katrina Danielle A Hernais, Thenknis T Camara, Michael B Ples, Rodel Jonathan S Vitor II
Comparison of efficacy of calcipotriol and betamethasone combination with betamethasone alone in plaque psoriasis
Background: Topical therapy constitutes the first line of management in mild to moderate psoriasis. Studies comparing the treatment outcome of topical calcipotriol and betamethasone dipropionate combination with betameth...
ED50 from anti-inflammatory properties of Vitex trifolia L. ethanol extract
Background: In Indonesia, Vitex trifolia grown as a crop or bush is even used as a guardrail. Conventionally, V. trifolia is used as a swelling drug caused by breast cancer by drinking the decoction of its leaves. Our gr...
Impact of chemotherapy with concurrent radiotherapy on quality of life in post-operative advanced head-and-neck cancer patients: A cross-sectional study
Background: Patients with head-and-neck cancer (HNC) have various challenging symptoms due to their disease and treatment side effects which again complicate the disease progress as it has a direct implication toward the...
High-dose cytarabine-associated cerebellar toxicity: A case report
High-dose arabinoside cytarabine is used as an effective regimen for post-remission acute leukemia and refractory leukemia treatment. Most commonly used regimen is 3 g/m2 IV over 1-3 h q12 h for a total of 8-12 doses. M...
Relationship between short-distance run and variables of pulmonary function tests
Background: The relationship of pulmonary functions and running performance has always been a topic of debate among the fraternity of physiologists. The relationship of submaximal exercise with lactate threshold,...