The Need for New Anti-Hepatitis C Virus Therapeutic Strategies Targeting the cellular micro-ribonucleic acids?
Journal Title: Sultan Qaboos University Medical Journal - Year 2010, Vol 10, Issue 3
Abstract
Infection with the hepatitis C virus (HCV) is a worldwide problem. Patients with chronic HCV infection who are non-responders to standard therapy represent a growing population within the HCV epidemic. Novel, more efcient and tolerable therapies are urgently needed. Tis review discusses the recent results showing that targeting miR-122, a micro-ribonucleic acid (MicroRNA) that enhances HCV replication, is a new anti-HCV therapy with a high barrier to resistance.
Authors and Affiliations
Elias A Said| Department of Microbiology & Immunology, Faculty of Medicine, Montreal University; Montreal, Quebec, Canada; and Montreal University Hospital Research Center (CR-CHUM), St-Luc Hospital, Montreal, Quebec, Canada
Keywords
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