The newly detected pulmonary sarcoidosis in HIV-infected patients
Journal Title: Туберкульоз, легеневі хвороби, ВІЛ-інфекція - Year 2019, Vol 0, Issue 1
Abstract
Objective — to determine the clinical, X-ray examination features in the newly detected sarcoidosis in HIV-infected patients. Materials and methods. Data of 6 HIV-infected patients (3 women, 3 men, middle age 42.4, range (28—61 years) with the newly detected sarcoidosis, that had been observed during 2006—2018 years. The level of CD4+-cells, signs or symptoms of disease, dependence of development of sarcoidosis on the terms of setting of АRT-treatment were considered. X-rays examinations (n = 6) and computer tomography (КТ) (n = 6) were performed, where next criteria: presence of lymphadenopathy, pulmonary nodules, interlobular septal thickening, focal consolidations, reticular opacities, ground glass opacity, cysts or fibrosis were considered. Results and discussion. The average interval between two diagnoses was 1 year. A level of CD4-cells s was 412 cells/µL (range of CD4+ 34—795 cells/µL). All patients had pulmonary signs or symptoms of sarcoidosis. X-rays examinations showed a lymphadenopathy, pulmonary nodules, focal consolidations, reticular opacities, ground glass opacity, and cysts. CТ scans showed a lymphadenopathy, pulmonary nodules, interlobular septal thickening, focal consolidations, reticular opacities, ground glass opacity. Conclusions. The X-ray examinations and clinical features in the newly detected pulmonary sarcoidosis in HIV-infected patients are analogical to sarcoidosis in nonHIVinfection patients. A level of CD4+-cells in most patients had more 200 cells/µL. Development of sarcoidosis depends from conservation or updating of level of CD4+ of lymph cells, and in the greater amount of cases, the level of CD4+ of lymph cells had been exceeded 200 cells/µL.
Authors and Affiliations
О. D. Nykolaeva
Keywords
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- EP ID EP606990
- DOI 10.30978/TB2019-1-52
- Views 93
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