The Rate of Pre-Eclampsia at Al-Wahda Hospital Derna, Libya: A Prospective Clinical Trial Study
Journal Title: Scholars International Journal of Obstetrics and Gynecology - Year 2018, Vol 1, Issue 4
Abstract
Pre-eclampsia, is an obstetric disorder characterized by hypertension and proteinuria that prevails all over the world. It presents as a pressing peril for fetal and maternal lives. Though inflammation, increased levels of TXA2, ischemic placenta, dysfunction of endothelium are discerned, the exact pathophysiology yet remains a mystery. The absolute treatment is still to be discovered, however its prevention by low dose aspirin and calcium supplementation present as promising preventative measures for pre-eclampsia. To observe the effect of aspirin and calcium in prevention of preeclampsia. This was a prospective clinical trial study for evaluation of role of aspirin and calcium in prevention of pre-eclampsia in primigravidas. It was carried out at department of Obstetrics and Gynecology at AL-Wahda hospital Derna from Jan 2016 to Dec 2016. Three hundred and forty four primigravidae were included in the study. Their age ranged from 16 to 45 years with a mean 26.32 ± 4.88 years. Out of the 344 healthy primigravidae, 63 (18.3 %) developed preeclampsia. Both (aspirin and calcium) supplementations were associated with a reduction preeclampsia. There was significant difference between the group taken both (aspirin & calcium) group and prevent pre-eclampsia (X2= 6.07, P= 0.014). In Conclusion, It was noted in the present study that low dose aspirin and calcium might have beneficial effect in the prevention of preeclampsia.
Authors and Affiliations
Soad Ajroud, Raga A. Elzahaf, Manal Younis
Keywords
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