The Reamberin’s Usage Effectiveness with the Purpose of Cognitive Functions’ Correction in the Acute Period of Polytrauma

Abstract

Injury is one of the causes of critical states and cognitive impairments development as well as their consequences. Cognitive impairments that occur in critical patients can not only significantly slow down the recovery process and worsen the quality of life after hospital, but also directly related to higher lethality. One of the important factors that oppress cognitive functions in traumatized patients may be posttraumatic stress disorder. Objective. The purpose of the article is to examine the reamberin’s effect on the cognitive functions’ state in the acute period in patients with polytrauma, not burdened by intracranial lesion. Materials and Methods: 49 patients were examined (26 in the control group and 23 in the main group). The level of cognitive functions before trauma was assessed by the CFQ questionnaire for 2-3 days after injury and in telephone mode 3 months after discharge; the MMSE scale was applied on the 2nd day in the intensive care unit, when transferring from the department and before discharge. The severity of the injury was assessed by the ISS scale. The severity of the response to traumatic stress was assessed by the IES-R scale. The data were processed using parametric and nonparametric statistics. Results. In both groups the baseline level of cognitive function was within the age range. Groups were comparable by age and severity of injury. In the early post-traumatic period, there was a significant decrease in cognitive functions in both groups according to baseline level. During treatment the inhibition of cognitive functions decreased. Cognitive function in the group receiving reamberin was slightly higher especially at the stage of transfer from the ICU, where this difference was statistically significant (p = 0.03). After 3 months the cognitive function in both groups decreased slightly relative to the level that was observed during discharge from the hospital. The psychological response to trauma and stress at the time of being in the intensive care unit was low in both groups. After 3 months the response to stress in both groups increased, with the initial difference with greater severity in the main group being replaced by an excess in the control group (the total in the main group increased by 15.8%, while in the control group it increased by 25.2%).

Authors and Affiliations

A. Krishtafor, L. Usenko, D. Krishtafor, M. Perederiy

Keywords

Related Articles

МОРФОЛОГІЯ ЛЕГЕНЕВИХ СУДИН ЩУРІВ МОЛОДОГО ВІКУ ЗА УМОВ ЕКСПЕРИМЕНТАЛЬНОГО АЛОКСАНОВОГО ДІАБЕТУ

Цукровий діабет – це захворювання, яке проявляється хронічною гіперглікемією та глюкозурією і супроводжується великою кількістю ускладнень з боку серцево-судинної та нервової систем. В статті описані зміни легеневих суди...

THE CHARACTERISTICS OF GAS-DISCHARGE GLOW OF A LIQUID FROM THE ACHILLES TENDON AND CHANGES OF INDIVIDUAL COMPONENTS IN THE LATE POSTMORTEM PERIOD

Many techniques have been proposed to establish the time of death. Most of them do not apply in the late postmortem period. It is necessary to search for new methods, which based on the evaluation of wellknown chemical a...

Pro- and Antiphlogistic Concentration of Cytokines in Rats’ Serum after Long-Term Administration of Omeprazole and the Simultaneous Injection of Multiprobiotics and Omeprazole

Nowadays, the literature data about the role of cytokines in stomach and intestines phlogistic processes develops against the backdrop of long hypoacidity of gastric juice in the absence of H. pylori infection is limited...

АУТОИММУННЫЙ ГЕМОЛИЗ У ПАЦИЕНТОВ С В-КЛЕТОЧНЫМИ НЕХОДЖКИНСКИМИ ЛИМФОМАМИ

При исследовании частоты встречаемости иммунных гемолитических осложнений при Вклеточных неходжкинских лимфомах выявлены антиэритроцитарные аутоиммунные антитела у 42,9% пациентов, принимавших полихимиотерапию без ритукс...

ОСОБЛИВОСТІ КЛІНІКО-МЕТАБОЛІЧНИХ ПОРУШЕНЬ ТА СТРУКТУРНО-ФУНКЦІОНАЛЬНИХ ЗМІН СЕРЦЯ У ХВОРИХ НА ГІПЕРТОНІЧНУ ХВОРОБУ З АБДОМІНАЛЬНИМ ОЖИРІННЯМ ТА ГІПЕРТРОФІЄЮ СЕРЦЯ

Було обстежено 82 хворих на гіпертонічну хворобу II стадії з абдомінальним ожирінням (з них – 66 хворих з гіпертрофією серця – основна група і 16 хворих – без гіпертрофії серця – група порівняння). Обсяг обстеження включ...

Download PDF file
  • EP ID EP273111
  • DOI -
  • Views 127
  • Downloads 0

How To Cite

A. Krishtafor, L. Usenko, D. Krishtafor, M. Perederiy (2017). The Reamberin’s Usage Effectiveness with the Purpose of Cognitive Functions’ Correction in the Acute Period of Polytrauma. Український журнал медицини, біології та спорту, 6(4), 75-81. https://europub.co.uk/articles/-A-273111