The Relationship Between Monocyte Count to High-density Lipoprotein Ratio and Severity of Inflammation in Aggressive Periodontitis: A Retrospective Analysis
Journal Title: Meandros Medical and Dental Journal - Year 2020, Vol 21, Issue 2
Abstract
Objective: Hyperlipidemia is a known cardiovascular disease risk factor. A common biological mechanism between systemic diseases, such as cardiovascular diseases, and periodontal diseases has been suggested. This study aimed to examine the association between blood lipid profile and the severity of aggressive periodontitis (AgP). Materials and Methods: A total of 32 systemically healthy patients with AgP (24 females and 8 males; mean age 34.78±6.42 years) were consecutively selected. The patients were divided into 2 groups as localised AgP (LAgP) and generalised AgP (GAgP). Monocyte counts, high-density level (HDL) count and monocyte/HDL ratios (MHR) were recorded from the patients’ blood samples. Mean Plaque index, bleeding on probing, periodontal pocket depth and clinical attachment level were recorded before treatment. The relationship between monocyte to HDL ratios and clinical attachment level between the groups were analysed by Spearman correlation. Results: Sixteen GAgP and 16 LagP patients were included in the study. The mean MHR values for the LAgP and GAgP groups were 9.87±2.85 and 13.43±4.64, respectively; there was a statistically significant difference between the groups (p<0.05). Conclusion: The increased MHR values in patients with severe periodontitis may be one of the pathogenic mechanisms underlying the link between periodontal and cardiovascular diseases. Although we observed statistically significant differences between the MHR values in both groups, a larger sample size is needed to confirm the results of this study in the future.
Authors and Affiliations
Berceste Güler, Ezgi Doğan, Kevser Onbaşı
Keywords
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- EP ID EP688731
- DOI 10.4274/meandros.galenos.2020.41033
- Views 133
- Downloads 0
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