The Relationship Between Monocyte Count to High-density Lipoprotein Ratio and Severity of Inflammation in Aggressive Periodontitis: A Retrospective Analysis
Journal Title: Meandros Medical and Dental Journal - Year 2020, Vol 21, Issue 2
Abstract
Objective: Hyperlipidemia is a known cardiovascular disease risk factor. A common biological mechanism between systemic diseases, such as cardiovascular diseases, and periodontal diseases has been suggested. This study aimed to examine the association between blood lipid profile and the severity of aggressive periodontitis (AgP). Materials and Methods: A total of 32 systemically healthy patients with AgP (24 females and 8 males; mean age 34.78±6.42 years) were consecutively selected. The patients were divided into 2 groups as localised AgP (LAgP) and generalised AgP (GAgP). Monocyte counts, high-density level (HDL) count and monocyte/HDL ratios (MHR) were recorded from the patients’ blood samples. Mean Plaque index, bleeding on probing, periodontal pocket depth and clinical attachment level were recorded before treatment. The relationship between monocyte to HDL ratios and clinical attachment level between the groups were analysed by Spearman correlation. Results: Sixteen GAgP and 16 LagP patients were included in the study. The mean MHR values for the LAgP and GAgP groups were 9.87±2.85 and 13.43±4.64, respectively; there was a statistically significant difference between the groups (p<0.05). Conclusion: The increased MHR values in patients with severe periodontitis may be one of the pathogenic mechanisms underlying the link between periodontal and cardiovascular diseases. Although we observed statistically significant differences between the MHR values in both groups, a larger sample size is needed to confirm the results of this study in the future.
Authors and Affiliations
Berceste Güler, Ezgi Doğan, Kevser Onbaşı
Keywords
Related Articles
- EP ID EP688731
- DOI 10.4274/meandros.galenos.2020.41033
- Views 158
- Downloads 0
Evaluation of Knowledge, Attitude and Behaviour on Oral Health Through COVID-19 Pandemic
Objective: This research is aimed at determining the changes in individuals’ knowledge, attitudes and behaviours regarding oral health in terms of nutritional habits, daily oral care and the provision of dental services...
Endovascular and Surgical Treatment of Acute Deep Vein Thrombosis
Acute deep vein thrombosis (DVT) has a high mortality and a significant morbidity risk. The most dreadful early complications of DVT are pulmonary embolism (PE) and phlegmasia cerulea dolens, which is a consequence of ci...
Evaluation of Complications Associated with Surgically Assisted Rapid Maxillary Expansion in Cases with or Without Pterygomaxillary Disjunction
Objective: Surgically assisted rapid maxillary expansion (SARME) is a widely used treatment method for the correction of transversal deficiencies of the maxilla. The gold standard treatment method among various surgical...
The Effects of Paracetamol and Ibuprofen on Smooth Muscle Response of the Bronchospasm: An In Vitro Study
Objective: Bronchospasm is a very important complication that can be encountered during the post-operative and intraoperative periods. This complication may be caused by surgery, anesthesia, or patient-related issues. Ma...
Micro-shear Bond Strength of Aged Resin Composite Repaired with Different Universal Adhesives
Objective: This study evaluated the effect of two different universal adhesives on the repair bond strength of aged resin composite. Materials and Methods: Forty-four composite resin disks were prepared (5 mm x 3 mm)....