The relationship of vitamin D status with serum ox- LDL in diabetes mellitus type 2
Journal Title: International Research Journal of Applied and Basic Sciences - Year 2013, Vol 4, Issue 11
Abstract
Theantioxidative role of vitamin D has been reported in previous studies. This study investigated the association between vitamin D status and serum ox-LDL in patients with diabetes type 2.This study conducted on 105 patients with diabetes type 2 including 57 ones with insufficient vitamin D status as cases and 48 ones with sufficient vitamin D status as controls. Weight and height were measured and body mass index (BMI) was calculated. Nutrients intake and daily sun exposure were assessed by questionnaire. Serum levels of lipid profile, oxidized-LDL (ox-LDL), calcium, phosphorus and 25-hydroxy vitamin D were measured.Total cholesterol (P=0.03), LDL-C (p=0.01) and LDL-OX (P=0.01) levels were significantly higher in patients with insufficient vitamin D status (P<0.001). No significant differences in triglycerides, HDL-C, intake of nutrients, daily sun exposure were found between two groups.Vitamin D may have a role in reduction of oxidative stress and free radicals in diabetes.
Authors and Affiliations
Mehdi Bahreini| School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran, Milad Daneshi Maskooni *| School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran, mi-daneshi@razi.tums.ac.ir, Mahmoud jalali| School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran, Elnaz Khorrami| School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran, Arvin Kashani| School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran, Mohammadreza Eshraghian| School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Mahnaz Zare| School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
Keywords
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