The Role of α-Defensins 1–3 in Antimicrobial Protection Forming in Children with Recurrent Bronchitis Caused by Bacteria of the Genus Haemophilus
Journal Title: Здоров`я дитини - Year 2013, Vol 2, Issue 45
Abstract
The level of α-defensins 1–3 (HNP 1–3) has been analyzed in the blood plasma of children with recurrent bronchitis caused by bacteria of the genus Haemophilus. It is shown that the level of HNP 1–3 in the blood plasma depends on the form of Haemophilus. Trigger of HNP 1–3 outflow for neutrophils was the presence of bacterial capsule while presence of L-forms of Haemophilus influenzae wasn’t associated with increase in synthesis of antimicrobial peptides that could be one of the factors of forming of Haemophilus antibiotic resistance.
Authors and Affiliations
G. O. Lezhenko, O. Ye. Abaturov, L. I. Pantyushenko
Keywords
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