The Role of α-Defensins 1–3 in Antimicrobial Protection Forming in Children with Recurrent Bronchitis Caused by Bacteria of the Genus Haemophilus
Journal Title: Здоров`я дитини - Year 2013, Vol 2, Issue 45
Abstract
The level of α-defensins 1–3 (HNP 1–3) has been analyzed in the blood plasma of children with recurrent bronchitis caused by bacteria of the genus Haemophilus. It is shown that the level of HNP 1–3 in the blood plasma depends on the form of Haemophilus. Trigger of HNP 1–3 outflow for neutrophils was the presence of bacterial capsule while presence of L-forms of Haemophilus influenzae wasn’t associated with increase in synthesis of antimicrobial peptides that could be one of the factors of forming of Haemophilus antibiotic resistance.
Authors and Affiliations
G. O. Lezhenko, O. Ye. Abaturov, L. I. Pantyushenko
Keywords
Related Articles
- EP ID EP233430
- DOI -
- Views 89
- Downloads 0
The influence of psycho-emotional stress in children of primary school age on the incidence of recurrent upper respiratory tract infections and the functional state of the myocardium
Background. Scientific and technical progress, intensification of educational process and information overload have a negative effect on unformed central nervous system of primary schoolchildren, causing stress, which af...
Alimentary water-nitrate methemoglobinemia in children in Ternopil region
This article considered the problem of spreading nitrate and nitrite contamination of the water and food, which leads to alimentary water-nitrate methemoglobinemia. Also, we presented the results of our research to show...
Place of Semisynthetic Penicillins and Macrolides in Antibiotic Therapy for Respiratory Infections in Children
The paper presents an overview of the guidelines for the treatment of respiratory infections by the Pediatric Infectious Diseases Society and Infectious Diseases Society of America (2011), the British Thoracic Society (2...
Case of a fatal lung disease in a child with juvenile dermatomyositis
The article presents a case of a fatal lung disease in a child with juvenile dermatomyositis. Juvenile dermatomyositis is a serious disease with an unpredictable course, and lung damage in juvenile dermatomyositis is one...
Features of Clinical Course of Perforated Ulcers of Stomach and Duodenum in Children
We examined 52 patients aged from 14 to 17 years with perforated ulcer of stomach and the duodenum, operated using laparoscopic and open ways. It is established, that perforated ulcer of stomach and the duodenum in child...