The Role of α-Defensins 1–3 in Antimicrobial Protection Forming in Children with Recurrent Bronchitis Caused by Bacteria of the Genus Haemophilus
Journal Title: Здоров`я дитини - Year 2013, Vol 2, Issue 45
Abstract
The level of α-defensins 1–3 (HNP 1–3) has been analyzed in the blood plasma of children with recurrent bronchitis caused by bacteria of the genus Haemophilus. It is shown that the level of HNP 1–3 in the blood plasma depends on the form of Haemophilus. Trigger of HNP 1–3 outflow for neutrophils was the presence of bacterial capsule while presence of L-forms of Haemophilus influenzae wasn’t associated with increase in synthesis of antimicrobial peptides that could be one of the factors of forming of Haemophilus antibiotic resistance.
Authors and Affiliations
G. O. Lezhenko, O. Ye. Abaturov, L. I. Pantyushenko
Keywords
Related Articles
- EP ID EP233430
- DOI -
- Views 64
- Downloads 0
The Role of Growth Factors (VEGF, TGF-β1) and Cyclic Guanosine Monophosphate in the Formation of Pulmonary Hypertension in Children with Bronchopulmonary Dysplasia
In 82 children with bronchopulmonary dysplasia (from 1 to 36 months of corrected age) we investigated the level of VEGF, TGF-β1 in blood and cyclic guanosine monophosphate (cGMP) in sputum. It was revealed that children...
eatures of Microelement Homeostasis in Children Living in the Modern City and Its Effect on the Immune System
Introduction. Recently, the issue of environmental pollution with various trace elements becomes increasingly important. Especially their adverse effects, even in small concentrations, on the health of children, in parti...
Hereditary and familial diseases and malformations of kidneys in childhood
The article presents the results of a review on the incidence and characteristics of the course of hereditary kidney diseases. According to the World Health Organization, the incidence of hereditary diseases and kidney a...
Features of violations of the lipid spectrum and components of the coagulation system in children with comorbid states in juvenile idiopathic arthritis
Background. In children and adolescents with juvenile idiopathic arthritis (JIA), a high immune-inflammatory activity of the disease leads to accelerated development of atherosclerosis and the comorbid pathology. Typical...
Acute Pharyngitis in Children: Issues of Etiology and Treatment
Article is devoted to the issues of rational treatment of acute pharyngitis in children with acute respiratory viral infections. Attention is given to herbal preparations, namely Tonsipret®, which has a pronounced analge...