The Role of Elastase Antibodies, Circulating Autoantibodies to Glutamate Decarboxylase and Islet Cells Antigens in Chronic Pancreatitis
Journal Title: Гастроентерологія - Year 2014, Vol 4, Issue 54
Abstract
The article presents an analysis of the occurrence of elastase antibodies, circulating autoantibodies to glutamate decarboxylase and islet cells antigens in different forms of chronic pancreatitis. In all patients with chronic pancreatitis we have detected a high frequency of circulating autoantibodies to GADA antigens, indicators of which are the highest in chronic pseudotumor and calculous pancreatitis. The presence of circulating autoantibodies to islet cell antigens is observed in all groups of patients, however, the highest rates were revealed in chronic parenchymatous and calculous pancreatitis. In 70 % of patients with chronic pancreatitis there are being detected elastase antibodies. In chronic pseudotumor pancreatitis with violation of excretory and endocrine functions of the pancreas we have revealed a significant increase in elastase antibodies. Increased elastase antibodies, circulating autoantibodies to glutamate decarboxylase and islet cells antigens in chronic pancreatitis may be indicative of the immune system stress that must be considered during the treatment.
Authors and Affiliations
V. Yu. Koval
Keywords
Related Articles
- EP ID EP225181
- DOI -
- Views 67
- Downloads 0
The role of gender dimorphism in the development and outcome of chronic viral hepatitis
Chronic viral liver diseases still have a leading place in the structure of mortality from hepatobiliary diseases and causes of liver transplantation. Search for factors influencing the progression of fibrosis and the pr...
Functional Features of the Pancreas during Chronic Pancreatitis
Aim of study: to identify functional status of pancreas in patients with chronic pancreatitis depending on the stage of fibrotic transformation and activity of parenchymal inflammation. Materials and methods. The preoper...
Clinical and sonographic features of the pancreatic steatosis in children with overweight and obesity
Background. Early diagnosis of pancreatic steatosis is essential for the early metabolic risk detection and chronic gastroenterological morbidity reduction. The purpose was to examine the clinical and sonographic feature...
Current State of Antibiotic Resistance to Helicobacter pylori and its Clinical Significance
The article presents an analysis of published data in recent years on the development and prevalence of Helicobacter pylori resistance to various antibiotics, which are used for the eradication of this microorganism. The...
Dynamics of COX-2 Content in Mucosa of the Stomach and Duodenum on the Background of Medical Correction of NSAID Gastropathy
The results of immune histochemical study of cyclooxygenase type 2 (COX-2) level in 120 patients with inflammatory and erosive lesions of the stomach and duodenum on the background of long-term use of non-steroid anti-in...