The Role of Elastase Antibodies, Circulating Autoantibodies to Glutamate Decarboxylase and Islet Cells Antigens in Chronic Pancreatitis
Journal Title: Гастроентерологія - Year 2014, Vol 4, Issue 54
Abstract
The article presents an analysis of the occurrence of elastase antibodies, circulating autoantibodies to glutamate decarboxylase and islet cells antigens in different forms of chronic pancreatitis. In all patients with chronic pancreatitis we have detected a high frequency of circulating autoantibodies to GADA antigens, indicators of which are the highest in chronic pseudotumor and calculous pancreatitis. The presence of circulating autoantibodies to islet cell antigens is observed in all groups of patients, however, the highest rates were revealed in chronic parenchymatous and calculous pancreatitis. In 70 % of patients with chronic pancreatitis there are being detected elastase antibodies. In chronic pseudotumor pancreatitis with violation of excretory and endocrine functions of the pancreas we have revealed a significant increase in elastase antibodies. Increased elastase antibodies, circulating autoantibodies to glutamate decarboxylase and islet cells antigens in chronic pancreatitis may be indicative of the immune system stress that must be considered during the treatment.
Authors and Affiliations
V. Yu. Koval
Keywords
Related Articles
- EP ID EP225181
- DOI -
- Views 62
- Downloads 0
Insulin Resistance, Its Role in the Development of Nonalcoholic Fatty Liver Disease in Patients with Metabolic Syndrome, Ways of Correction
The article presents data on the role of the liver in carbohydrate and lipid metabolism, describes glucose metabolism features in insulin resistance and the role of glucokinase pathways of glucose uptake in the hepatocyt...
Negative effects of abuse of laxatives in medical practice
The abuse of laxatives is a disorder characterized by an incomprehensible and changing range of gastrointestinal, electrolytic and acid-base abnormalities that can lead to both the onset of chronic diseases and fatalitie...
First district sanitary doctor of Katerynoslav
The life and professional activity of Vasyl Tymofiiovych Skrylnikov — a famous doctor-hygienist, scientist, and public figure have been represented. V.T. Skrylnikov contributed to the development of sanitary-prophylaxis...
Value of Fecal Calprotectin in Rotavirus Infection in Infants
The article presents results of a study of calprotectin level in faeces in infants with rotavirus. The aim of this study was to determine the value of fecal calprotectin concentration fluctuations in rotavirus infection...
Gastroenterological masks of partial epilepsy in clinical practice
The purpose of this paper is to draw gastroenterologists’ attention and underline the necessity to conduct detailed differential diagnosis in patients with dyspepsia syndrome. This paper shows a clinical case of abdomina...