The role of haematological parameters in predicting filariasis with special emphasis on absolute eosinophil count: A single Institutional experience.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11
Abstract
Introduction: Filariasis is a major public health problem in tropical countries, including India. A majority of infected individuals in filarial endemic communities are asymptomatic. The absolute eosinophil count (AEC) is known to have a good predictive value in the management of filariasis. Aims and Objectives: We aim to study the various haematological parameters and ascertain the predictive value of AEC in the detection of filariasis. We have also studied the pattern of presentation of the parasite on blood smears with respect to periodicity and its localisation in the smear. Materials and Methods: A prospective cross sectional study was conducted at a tertiary care hospital between the period of 2 years from September 2015 to August 2017. A total of 88 smear positive filarial patients and a control group of 100 patients of fever who were smear negative on three occasions were included. Hemoglobin, Total leucocyte count, Differential leucocyte count, platelet counts and absolute eosinophil counts were obtained. The data was analysed by statistical tools. Results: All the smear positive cases were caused by the Wuchereria bancrofti. Majority of the parasites were detected in the night blood samples taken between 8pm to 11pm. The parasites were found to be on the tail end of a thin blood film. In the present study, AEC was not found to have significant association with filaria. Conclusion: Although AEC is a useful marker for inflammation in many allergic and parasitic conditions, it cannot be treated as the sole predictive marker for filariasis and all the routine blood smears irrespective of the eosinophil counts need to be inspected on low power objective (40X) for presence of microfilariae especially near the tail end of the smear.
Authors and Affiliations
Sangita Bohara, Neeraj Tripathi, Rumpa Das, Monilisa Jha, Vivek Gupta
Keywords
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- EP ID EP409183
- DOI 10.9790/0853-1711032427.
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