The role of immunoglobulins in supportive treatment for patients with lymphoid neoplasms
Journal Title: Postępy Nauk Medycznych - Year 2012, Vol 25, Issue 9
Abstract
Lymphomas are derived from lymphoid cells at different levels of maturation. The cells of this system are the basic elements of immune responses, both cellular and humoral immune response. All these neoplasms are accompanied by immune disorders, often with hypogammaglobulinemia. Immunoglobulin affect all immune effector cells. Infection complications remain a major problem in this group of patients. Regular substitution in primary as well as secondary immunodeficiency is designed to reduce the incidence of infections, particularly bacterial and mitigate their clinical course. Immunomodulatory properties of immunoglobulins are used to treat the autoimmune process of Lymphoid Malignancies. Currently, new drugs allow the prolongation of survival in many cases of patients with lymphoma. Special attention should be paid to supportive care with immunoglobulin as substitution therapy, as well as immunomodulatory effects.
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Iwona Wyleżoł
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