The Role of Russian Scientists in the Development of Anthrax Vaccines
Journal Title: Актуальна інфектологія - Year 2015, Vol 3, Issue 8
Abstract
In Russia in the second half of the XIX century, research schools developing anthrax vaccines for agriculture were formed. According to their level, they are not inferior to similar Western schools. At the end of the 1930s, Soviet military scientists were the first in the world to create the anthrax vaccine on the basis of the spores of unencapsulated live strains of Bacillus anthracis for medical use. In the 1940–1960s, domestic scientists determined the principles of the development of anthrax vaccines, which enabled to avoid failures of their Western colleagues, when developing the vaccines capable of protecting the population from biological weapons with anthrax spores as the harmful agent. Russian military scientists in the 1990s managed to keep the vaccine strains of anthrax bacteria and to restore the technological capability for their manufacture, which helps to protect the population of the Russian Federation from natural anthrax outbreaks and from biological terror. At a time when there is a need in creating immunity in humans against infection caused by inhalation of anthrax spores, the most reasonable decision for the upcoming decades is to use the domestic combined vaccine that combines unencapsulated live strains of B.anthracis and anthrax toxin protective antigen.
Authors and Affiliations
M. V. Supotnytskyi, I. V. Borysevych, V. I Klymov, O. M Shevtsov, M. Yu. Lub, A. S. Tumanov
Keywords
Related Articles
- EP ID EP214380
- DOI -
- Views 102
- Downloads 0
Unfavorable outcome of herpes meningoencephalitis in an adolescent
A clinical observation of a severe form of herpes meningoencephalitis in 15-year-old adolescent is presented. Late diagnosis of meningoencephalitis and untimely administration of specific antiviral therapy (acyclovir was...
Infectious diseases in emergencies. Triaging of infectious patients
This article contains data on infectious diseases that usually develop in natural emergencies. Main questions regarding the triaging of infectious patients were analyzed.
Features of General Reactive Potential of the Body in Infants with BCG lymphadenitis
Objective: integrated health assessment of infants with BCG-induced regional lymphadenitis. Material and Methods. The work was carried out on the academic basis of pediatric infectious departments of Donetsk region and D...
Towards the Causation in Medicine
Ideas of monocausation in the development of infectious diseases are opposed to the reflections, according to which the «cause» concept includes the causative agent of infectious disease, genetic conditions necessary for...
The use of mathematical modeling in the epidemiological surveillance of acute intestinal infections
Background. Acute intestinal infections remain actual diseases for many countries of the world now, especially with middle and low income, in spite of improving sanitary and hygienic conditions of living, drinking water...