The study of phenolic compounds and the antimicrobial action of the alcoholic extract from the cake of the red raspberry fruit
Journal Title: Вісник фармації - Year 2018, Vol 95, Issue 3
Abstract
Aim. To study the antimicrobial action and the quantitative content of phenolic compounds of the alcoholic extract from the cake of the red raspberry fruit (Rubus idaeus).Materials and methods. The object of the study was the extract obtained from the fruit of Rubus idaeus. The content of phenolic compounds was determined by the spectrophotometric method. The study of the antibacterial activity of the extracts was carried out by the agar diffusion method.Results and discussion. It has been found that the content of hydroxycinnamic acid derivatives is 2.21 ± 0.02 %, flavonoids – 0.82 ± 0.01 %, and the amount of phenolic compounds is 4.52 ± 0.02 % in the extract of the red raspberry fruit. The results of the studies conducted have shown that the test sample of the extract from the raspberry fruit has a wide range of the antimicrobial activity, including the antibacterial and antifungal activity.Conclusions. By studying the antimicrobial activity the possibility of creating a new antimicrobial drug based on the raspberry fruit has been proven. The content of phenolic compounds in the extract from the cake of the red raspberry fruit has been studied.
Authors and Affiliations
I. M. Polischuk, О. М. Koshovyi, T. P. Osolodchenko, M. А. Komissarenko
Keywords
Related Articles
- EP ID EP668905
- DOI 10.24959/nphj.18.2220
- Views 97
- Downloads 0
The study of acute toxicity of 1,3-oxazole-4-il-phosphonic acid derivative in intraperitoneal administration
The derivative of 1,3-oxazole-4-yl-phosphonic acid (OVP-1) has the vasodilatory activity and is studied as a potential antihypertensive agent. The toxicological assessment plays an important role in the preclinical study...
A social significance of the pharmacogenetic testing in Ukraine on the example of the CYP2B6 gene participating in the nicotine metabolism
The study of the pharmacogenetic testing in Ukraine on the example of the gene CYP2B6 participating in the nicotine metabolism is currently topical and socially significant problem. Aim. To determine the potential sample...
A comprehensive analysis of prescribing drugs for the treatment of cardiovascular diseases in a clinical setting
Aim. To assess comprehensively the actual use of drugs for the treatment of the cardiovascular system, which cost is subject to the state reimbursement in a clinical setting. Materials and methods. The list of medicines...
Синтез и исследование антиоксидантной и противовоспалительной активности моно- и бис-производных спиро-2-оксиндол[3,3’]пиррола
Цель работы – синтез ряда моно- и бис-производных спиро-2-оксиндол[3,3’]пиррола и исследование их антиоксидантной и противовоспалительной активности. Материалы и методы. Методы органического синтеза, инструментальные мет...
Дослідження стабільності супозиторіїв з рослинним комплексом гліфазин у процесі зберігання
Результатом цілеспрямованого пошуку у напрямку створення ефективного і безпечного лікарського засобу (ЛЗ) для лікування цукрового діабету (ЦД) 2 типу стала розробка супозито-ріїв з рослинним комплексом гліфазин, який отр...