The study of the assorment of dermatological products for the local treatment of seborrheic dermatitis
Journal Title: Соціальна фармація в охороні здоров’я - Year 2018, Vol 4, Issue 3
Abstract
Aim. To perform the analysis of the assortment of medicines, in particular dermatological agents for the treatment of seborrheic dermatitis, which are present at the domestic pharmaceutical market with the subsequent substantiation of the need to develop a new foaming agent. Materials and methods. The analysis was based on the data of the State Register of Medicinal Products of Ukraine, electronic databases, “Morion” information retrieval program. The logical, system-analytical, comparative methods of analysis were used in the work. Results. The analysis of the drugs belonging to D01A group “Antifungal preparations for topical administration”, namely the subgroups: D01A C – “Imidazole and triazole derivatives” and D01A E – “Other antifungal agents for topical application” registered at the Ukrainian market has shown that the leading positions are in the subgroup D01A C – “Imidazole and triazole derivatives” (71 %), while the group D01A E – “Other antifungal agents for topical application” has only 29 %. It has been found that the composition of the drugs studied includes 8 synthetic active substances. Derivatives of imidazole, pyrithione, allylamines are the most frequently used. It has been determined that among these medicines monopreparations predominate; some of them are 88 % of the total number of trade names, while only 12 % are combined drugs. Further study of the assortment of the registered producers of antifungal agents for local application by manufacturing countries has shown that 13 countries are registered at the Ukrainian market: India (35 %), Ukraine (32 %), Switzerland (6 %), Belgium, Germany and Turkey (4 %), Spain and Belgium (3 % each). All other manufacturing countries are represented by 2 %. It has been noted that the soft dosage form predominates in the structure of the drugs under study, namely creams – 41 %, ointments – 12 %, gels – 15 %; liquid forms are shampoos – 16 %, solutions for external use – 8 %, spray – 6 %; and there are only 2 % of solids. Conclusions. Based on the data of the State Register of Medicinal Products of Ukraine it has been found that the total number of drugs of group D01A “Antifungal preparations for topical administration” is 51 trade names. It has been noted that 8 active substances of synthetic origin are presented in the form of monopreparations (88 %) or in combination (12 %) with each other. It has been found that the ratio between imported and domestic medicines is 68 %: 32 %. It has been determined that 41 % of the drugs registered are produced in the form of a cream, 16 % in the form of a shampoo, 15 % in the form of a gel and 12 % in the form of an ointment, while a small part of the preparations is in the form of a solution, a spray and a powder.
Authors and Affiliations
S. V. Zaika, Yu. O. , Bezpala, K. S. Shmelkova, O. P. Shmatenko
Keywords
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- EP ID EP671029
- DOI 10.24959/sphhcj.18.124
- Views 149
- Downloads 0
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