The TyG index cutoff point and its association with body adiposity and lifestyle in children
Journal Title: Jornal de Pediatria - Year 2019, Vol 95, Issue 2
Abstract
Objective To investigate the factors associated with insulin resistance in children aged 4–7 years, and to identify the cutoff point of the triglyceride-glucose index for the prediction of insulin resistance in this population. Methods A cross-sectional study was conducted with 403 children from a retrospective cohort. Insulin resistance was also evaluated in a sub-sample using the HOMA index. Four indicators of body adiposity were assessed: body mass index, waist-to-height ratio, and the percentages of total and central body fat. Food habits were evaluated by the identification of dietary patterns, using principal component analysis. Information was also collected on lifestyle, socioeconomic status, and breastfeeding time. Results The median index observed in the sample was 7.77, which did not differ between the genders. The shorter the time spent in active activities, the higher the triglyceride-glucose value; and increase in the values of body adiposity indicators was positively associated with triglyceride-glucose. The cutoff point with the best balance between sensitivity and specificity values was 7.88 (AUC=0.63, 95% CI: 0.51–0.74). Conclusion The present study identified that total and central body adiposity and shorter time spent in lively activities was positively associated with insulin resistance, evaluated through the triglyceride-glucose index. The cutoff point of 7.88 may be used in this population for insulin resistance risk screening, but caution is required when using it in other populations.
Authors and Affiliations
Sarah Vieira-Ribeiro
Keywords
Related Articles
- EP ID EP497489
- DOI 10.1016/j.jped.2017.12.012
- Views 47
- Downloads 0
Bullying behavior, youth's disease and intervention: which suggestions from the data for research on bullying in the Brazilian context?
Since the influential work by Dan Olweus,1 bullying has emerged as a major problem of the society all over world and across societies. The international literature reports rates of children and adolescents involved in bu...
Analysis of analgesic, antipyretic, and nonsteroidal anti-inflammatory drug use in pediatric prescriptions
Objective Data on clinical practice in pediatrics on the use of analgesic, antipyretic, and nonsteroidal anti-inflammatory drugs considering the best available evidence and regulatory-agency approved use are uncertain. T...
Birth weight and its association with blood pressure and nutritional status in adolescents
Objective The management of children with low birth weight is not the same in countries with different resources. The authors assessed the association of birth weight with blood pressure and nutritional status in a repre...
Energy expenditure, growth, and nutritional therapy in appropriate and small for gestational age preterm infants
Objective To evaluate the resting energy expenditure, growth, and quantity of energy and macronutrients intake in a group of preterm newborns. Methods The cohort study was performed with appropriate and small for gestat...
Maternal food intake and socioeconomic status to tackle childhood malnutrition
This issue features a study by Géa-Horta et al.,1 which describes the association between maternal socioeconomic factors (employment and level of schooling) and the occurrence of some nutritional indicators (short statur...