The use of fine needle aspiration biopsy in the diagnosis of thyroid nodules
Journal Title: Postępy Nauk Medycznych - Year 2014, Vol 27, Issue 10
Abstract
Introduction. Fine needle aspiration (FNA) is a simple, inexpensive, easily performed outpatient procedure which can provide a rapid diagnosis. It is eminently suitable for the investigation of superficial palpable lesions in many sites, including the thyroid gland. Cytological examination of aspirated material can detect thyroiditis, toxic hyperplasia and colloid goiters as well as neoplastic processes, epithelial, lymphoid and metastatic changes.Aim. The aim of this study was the analysis of the results of FNAB in thyroid nodules in children, the usefulness of FNAB in the therapeutic procedures and comparison of the cytologic changes with the postoperative changes of the thyroid.Material and methods. Thirty seven patients (33 females and 4 males) of the Clinical Department of Endocrinology and Pediatrics in the Warsaw University of Medicine, were qualified to FNA because of the presence of thyroid nodules. The age of patients varied from 7 to 18 years old. The microscopical changes were described according the cytological picture and graded by recommended diagnostic categories using Bethesda System.Results. In most patients (31/37) the results of FNA were consistent with the grade 2 according to Bethesda System, in one patient with the grade 1, in two patients with the grade 3, in another two patients with the grade 5, and finally in one patient with the grade 6 corresponding to papillary carcinoma. The patients presented in the article did not follow the core needle biopsy, but we have demonstrated that in our group of patients FNA was a sensitive test. The results of FNA coincided with the histopathological results of surgical specimens.Conclusions. We have demonstrated that the main purpose of this technique is to provide a differential diagnosis between benign and malignant changes enabling appropriate therapeutic management and the determination of the correct surgical procedure when surgery is required.
Authors and Affiliations
Magdalena Grajewska-Ferens, Joanna Cielecka-Kuszyk
Keywords
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