The value of positron emission tomography as diagnostic procedure in epilepsy
Journal Title: Postępy Nauk Medycznych - Year 2013, Vol 26, Issue 10
Abstract
Radioisotope methods belong to the best evidence for metabolic processes in the brain. Positron emission tomography (PET) is the basic method that allows to molecular imaging. The advantage of this method is the ability to provide the minimum amount of radioactive atoms labelled physiological molecules, with a very short half-life, in order to obtain information about the processes occurring at the cellular level. It is possible to show chandes in radioisotope markers as 10-11 mol. The most usefull, universal radioisotope is 2-fluoro-2-deoksy-D-glukose (18F-FDG), but in different neurological disorders other markers are also used. PET study allows to differentiate between physiological and pathological accumulation of the marker. PET is the most often used in oncology, neurology and cardiology. It is estimated that approximately 63% of the patients with epilepsy has the diagnosis set by using different diagnostic methods (computer tomography, magnetic resonance imaging, SPECT, PET) to show the focal morphological abnormalities in the nervous tissue. The use of PET as the diagnostic test in epileptic patients is increasingly regarded as standard, especially in the case of focal and drug-resistant seizures. The conclusion was stressed that the complementary diagnostic procedures give the best way of complete look for patient.
Authors and Affiliations
Ewa Nagańska
Keywords
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