Therapeutic effect of intraovarian injection of autologous platelet-rich plasma for the treatment of diminished ovarian reserve
Journal Title: Chinese Journal of Blood Transfusion - Year 2024, Vol 37, Issue 9
Abstract
Objective To explore the effectiveness of intraovarian injection of platelet-rich plasma(PRP) in the treatment of patients with diminished ovarian reserve(DOR), aiming to provide new diagnostic and therapeutic ideas for the treatment. Methods A total of 22 patients with DOR who underwent autologous PRP ovarian injection at the Reproductive Medical and Genetic Center of Qinzhou Maternal and Child Health Hospital from January 2021 to December 2023 were collected. Among them, 12 patients underwent assisted reproductive technology for pregnancy. The patient′s anti-Müllerian hormone (AMH), antral follicle count (AFC), basal follicle-stimulating hormone (FSH), basal luteinizing hormone (LH) and basal estradiol (E2) levels were observed. Results The levels of AMH, AFC, basal FSH, basal LH and basal E2 in 22 patients improved after treatment compared with those before treatment. Of the 12 patients who received assisted reproduction, 2 had IVF cycle canceled due to poor ovarian reaction. Ten patients obtained embryos, of which 5 obtained high-quality embryos. Conclusion Intraovarian injection of autologous PRP can effectively improve ovarian reserve function in patients with DOR.
Authors and Affiliations
Hongbo WU, Yanmei LIU, Zhao ZHANG, Liling LIU
Keywords
Related Articles
- EP ID EP748044
- DOI 10.13303/j.cjbt.issn.1004549x.2024.09.005
- Views 43
- Downloads 0
Shanghai expert consensus on remote verification system of blood distribution in medical institutions
In order to solve the difficulties and challenges in the implementation of the original blood distribution and collection regulations caused by the expansion of hospital area, the extension of blood transfer time, the ch...
Application of serum plate in the grey area setting of HBsAg ELISA
Objective To evaluate the necessity and rationality of setting 0.7 CO of the gray area of HBV surface antigen reagent (ELISA) in our laboratory, and to provide the basis for the grey area setting. Methods A total of 60 s...
Matching strategy for patients with platelet transfusion refractoriness caused by compound antibodies against HLA and CD36
Objective To search compatible and suitable platelets for platelet transfusion refractoriness (PTR) patient caused by compound antibodies against HLA and CD36. Methods ELISA method was used to detect the antibody against...
Effect of long-term frozen plasma on the detection of HBsAg by ELISA
Objective To evaluate the HBsAg detection results of HBsAg+ samples after 8 years refrigeration by ELISA and evaluate the effectiveness of the current storage policy of retained samples. Methods A total of 100 HBsAg+ pla...
In vitro quality evaluation of leucocyte-reduced pooled platelet concentrates prepared from whole blood stored at 4℃
Objective To investigate the feasibility of leucocyte-reduced pooled platelet concentrates from whole blood stored at 4℃, and provide theoretical basis for the components preparation. Methods The collected 400 mL ACD-B a...