Therapeutic Effects of Green Tea on Nonalcoholic Fatty Liver Disease in 10-16-Year-Old Children
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 7
Abstract
ABSTRACT Introduction: Nonalcoholic Fatty Liver Disease (NAFLD) is characterised by fat accumulation in the liver. Treatment of NAFLD in children is an important issue but the options are limited. Green tea has antioxidant and anti-hyperlipidemic effects but studies; on the effect of green tea in children are limited. Aim: To investigate effect of green tea on NAFLD in children. Materials and Methods: In this study, 52 children aged 10-16 years with NAFLD were divided into two groups of 26 each: Intervention and control. For both groups, modification of diet and intensification of physical activity were prescribed for three months. Intervention group was also treated with green tea tablets. Sonography and measurements of liver enzymes {Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST)}, lipid profile and Body Mass Index (BMI) were conducted before and after the intervention. The data were analysed by the Statistical Package for the Social Sciences (SPSS) version 19.0 using ANCOVA. Results: After treatment with green tea, fatty liver grade decreased significantly in the intervention group compared to control group (p<0.0001). In addition, this treatment caused significant decrease in ALT, AST, and triglyceride levels and significant increase in High-Density Lipoprotein (HDL) level (p<0.05), but Low-Density Lipoprotein (LDL) level did not decrease significantly in the intervention group compared to control. Conclusion: Oral prescription of green tea was effective in improving fatty liver grade, decreasing hepatic fat accumulation and improving liver function, weight loss and reducing ALT and AST without any side effects. These effects can be due to green tea compounds such as polyphenols especially catechin and antioxidant and anti-hyperlipidemic effects.
Authors and Affiliations
Noushin Rostampour, Karam Ali Kasiri, Elham Hashemi-Dehkordi, Abdol Majid Taheri, Anahita Farahzad Broujeni, Mahmoud Rafieian-Kopaei
Keywords
Related Articles
- EP ID EP606997
- DOI 10.7860/JCDR/2019/35236.12986
- Views 118
- Downloads 0
Profile of Inflammatory Bowel Disease in a Tertiary Care Centre of Eastern Nepal
ABSTRACT Introduction: Inflammatory Bowel Disease (IBD) is a chronic, relapsing inflammatory disorder of gastrointestinal tract that encompasses chronic Ulcerative Colitis (UC) and Crohn’s Disease (CD). Traditionally, it...
Prevalence of Autonomic Neuropathy in Patients of Rheumatoid Arthritis and Its Correlation with Disease Severity
Introduction: Autonomic Neuropathy (AN), found to be a strong predictor of sudden cardiac death, has been reported variably in patients with Rheumatoid Arthritis (RA). Manifesting as sweating disturbances, gastrointestin...
Orbital Myiasis with Scalp Pediculosis and Buccal Abscess– An Uncommon Presentation
We present a case of severe orbital myiasis caused by Osteris ovis, also known as sheep nasal botfly which is an uncommon manifestation of maggot infestation. Our patient was successfully treated with oral as well as top...
Autism Spectrum DisordersAetiopathogenesis
Autism Spectrum Disorders (ASD) are characterised by a range of clinical features that can vary from individual to individual in both degree of severity and variability of the clinical presentation. The aetiology or caus...
Management of Flabby Tissue with Reinforcement of Metal Mesh in Custom Tray
ABSTRACT Patients with flabby tissue require impression procedures which will record the entire denture bearing area in a functional form and the flabby tissue in undisplaced form. This article presents simple and practi...