Therapeutic Effects of Green Tea on Nonalcoholic Fatty Liver Disease in 10-16-Year-Old Children
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 7
Abstract
ABSTRACT Introduction: Nonalcoholic Fatty Liver Disease (NAFLD) is characterised by fat accumulation in the liver. Treatment of NAFLD in children is an important issue but the options are limited. Green tea has antioxidant and anti-hyperlipidemic effects but studies; on the effect of green tea in children are limited. Aim: To investigate effect of green tea on NAFLD in children. Materials and Methods: In this study, 52 children aged 10-16 years with NAFLD were divided into two groups of 26 each: Intervention and control. For both groups, modification of diet and intensification of physical activity were prescribed for three months. Intervention group was also treated with green tea tablets. Sonography and measurements of liver enzymes {Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST)}, lipid profile and Body Mass Index (BMI) were conducted before and after the intervention. The data were analysed by the Statistical Package for the Social Sciences (SPSS) version 19.0 using ANCOVA. Results: After treatment with green tea, fatty liver grade decreased significantly in the intervention group compared to control group (p<0.0001). In addition, this treatment caused significant decrease in ALT, AST, and triglyceride levels and significant increase in High-Density Lipoprotein (HDL) level (p<0.05), but Low-Density Lipoprotein (LDL) level did not decrease significantly in the intervention group compared to control. Conclusion: Oral prescription of green tea was effective in improving fatty liver grade, decreasing hepatic fat accumulation and improving liver function, weight loss and reducing ALT and AST without any side effects. These effects can be due to green tea compounds such as polyphenols especially catechin and antioxidant and anti-hyperlipidemic effects.
Authors and Affiliations
Noushin Rostampour, Karam Ali Kasiri, Elham Hashemi-Dehkordi, Abdol Majid Taheri, Anahita Farahzad Broujeni, Mahmoud Rafieian-Kopaei
Keywords
Related Articles
- EP ID EP606997
- DOI 10.7860/JCDR/2019/35236.12986
- Views 121
- Downloads 0
Prevalence of Intestinal Parasitic Infections among Pulmonary Tuberculosis Patients in a Tertiary Care Hospital, Bhubaneswar, Odisha, India
ABSTRACT Introduction: In developing countries like India, Intestinal Parasitic Infections (IPIs) and Tuberculosis (TB) co-infection have been perceived to be high. The geographic distributions of helminths and TB overla...
Probiotics in the Prevention of Antibiotic Associated Diarrhoea in a Tertiary Teaching Hospital in Pokhara: A Prospective Study
Introduction: Diarrhoea is an undesirable side effect when treating common infections in children with antibiotics. Though studies have shown the effectiveness of probiotics in preventing antibiotic associated diarrhoea,...
A Diagnostic Surprise For A Right Iliac Fossa Mass – A Perforated Ileal Gastrointestinal Stromal Tumour
Gastrointestinal Stromal Tumours (GISTs) are tumours of the gut found mostly in stomach and small intestine. The complications are Gastrointestinal (GI) bleeding, obstruction, pain and rarely perforation. We are reportin...
Identifying the Challenges and Cost-effectiveness of Telerehabilitation: A Narrative Review
ABSTRACT Technology has been evolving at an exponential speed in the past decade and the evidence of a dramatic change is all around us such as self-driving cars, artificial intelligence, robotics, and many more. The fus...
Enhanced Inflammatory Status in Patients with Simple Central Obesity in Absence of Metabolic Syndrome
ABSTRACT Introduction: Abdominal obesity is associated with cardiovascular risk factors. Metabolic Syndrome (MS) describes a constellation of metabolic abnormalities, including abdominal obesity. However, there is limite...