Therapeutic Management of Benign Prostatic Hyperplasia: From Synthetics to Naturals
Journal Title: Annual Research & Review in Biology - Year 2017, Vol 17, Issue 5
Abstract
Benign prostatic hyperplasia (BPH) is a common urological disorder of men with multi-factorial etiology, particularly affecting the lifestyle of elderly patients. Sex steroid hormones essential for the development and growth of normal prostate are recognized as major risk factors, though many others such as aging, genetic, diet, hypertension, obesity, smoking, alcohol and physical activity have been identified as playing a significant role. Depending on the stage of BPH, and complications involved, the treatment includes different classes of synthetic drugs and/or surgery while some phytotherapeutic agents also represent the first line of treatment. Numerous plant extracts, fruits, and beverages are used alone or in combinations for the management of BPH with few having emerged as the choicest treatment. The public interest in natural agents is largely because of the side effects related to synthetics and a general fear of morbidity arising out of surgery. The phytotherapeutic agents represent the most promising and safe alternative as antiBPH agents signifying a strong area for further exploration by medicinal chemists. This review provides a complete insight on the epidemiology, pathophysiology, various risk factors involved, and different therapeutic approaches available. A brief outline of the surgical and synthetic treatment with detailed note on phytotherapeutics as the treatment options for the prevention and management of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS) is provided.
Authors and Affiliations
Ashish Kumar Jena, Karan Vasisht, Maninder Karan
Keywords
Related Articles
- EP ID EP313430
- DOI 10.9734/ARRB/2017/35896
- Views 113
- Downloads 0
Effects of Chromium on Human Body
Chromium is widely used in medical and dental implants, appliances and tools, where sufficient content s of this chemical element can provide a protective corrosion-resistant oxide on the alloy surface. At low concentrat...
Extrapolation of the Species Accumulation Curve Associated to “Chao” Estimator of the Number of Unrecorded Species: A Mathematically Consistent Derivation
Incomplete samplings are doomed to become common practice for many inventories of biodiversity, thereby inviting to extrapolate what the rate of accumulation of newly recorded species would be if sampling was to be conti...
Biotic Factors Affecting the Abundance of Vascular Epiphytic Bromeliads Growing in Cloud Forest in Reserva Biologica Los Cedros, Ecuador
Aims: In this paper we investigate whether the abundance of epiphytic bromeliads growing in cloud forest was affected by: (1) phorophyte family; (2) phorophyte size; and (3) the abundance of other epiphytes. Study Design...
Death Feigning Behaviour of Several Frog Species from Kedah, Peninsular Malaysia
Two individuals of ranid species, Hylarana picturata and Hylarana laterimaculata, were collected from Sungai Sedim Recreational Forest. A single individual of dicroglossid species, Occidozyga laevis and two individuals o...
Photochemical oxidation of γ-exachlorocyclohexane and 4,4’- dichlorodiphenyldichloroethylene
Objectives: Utilization of the forbidden organochlorine pesticides demands searching of new ways of their neutralization. In such way there can be a photochemical oxidation of pesticides. As a re...