Thrombocytopenia versus SOFA to predict mortality in patients with sepsis in the Intensive Care Unit of a tertiary hospital in Guatemala
Journal Title: Revista Científica Facultad de Ciencias Químicas y Farmacia - Year 2019, Vol 29, Issue 1
Abstract
The most common coagulation disorder in the intensive care unit is thrombocytopenia. Considering the fundamental role of platelets in hemostasis and as markers of disseminated intravascular coagulation, a significant decrease in platelet count is alarming in the context of septic patients, and it is known to be a predictor of death. The objective was to compare the ability of the platelet count with the Sequential Organ Failure Assessment (SOFA) to predict death in patients with severe sepsis or septic shock. A longitudinal study was conducted with a sample of 29 consecutive cases evaluated during January to December 2015 in the Intensive Care Unit of the General Hospital of Diseases (HGE) of the Guatemalan Social Security Institute. Platelet and SOFA counts were performed at the first and the fifth day of hospitalization, documenting the outcome of the patients. Of the total, 51.7% of the patients were men and 48.3% were women, with an average age of 62.0 (16.9) years, median SOFA on admission of 10 units (Q1=4, Q3=14), and platelet median on admission of 196000 (Q1=100000, Q3=250000). The univariate association between thrombocytopenia and death was significant (p = .021, RR = 2.45, CI 95% [1.21, 4.99]). According to a Bootstrap test, there is no significant difference between the predictive capacity of SOFA and platelet count (p = .965). It was concluded that the presence of thrombocytopenia is a simple predictor of death in patients with severe sepsis or septic shock, with similar capacity to SOFA
Authors and Affiliations
Escobar Jímenez, Nancy; Ranero Meneses, Jorge; Chocó-Cedillos, André
Keywords
Related Articles
- EP ID EP675520
- DOI -
- Views 210
- Downloads 0
Editorial 29 /2)
La actual coyuntura de emergencia sanitaria, ha verificado el valor del impacto de la inversión de tiempo y trabajo en la elaboración y actualización del sitio Web de la Revista Científica, situación que permitió estar...
Potencial de los hongos anamorfos de Guatemala para la producción de α-amilasas utilizando como sustrato cascarilla de arroz Guatemalan anamorphic fungi and their potential use in production of α-amylases using rice husk as a substrate
Los desechos agroindustriales se generan en grandes cantidades, y en la mayoría de los casos son depositados en vertederos lo cual constituye un problema ambiental. Estos residuos lignocelulósicos pueden utilizarse como...
Caracterización de carbapenemasas en enterobacterias de muestras de pacientes que acudieron al Hospital General San Juan de Dios de la ciudad de Guatemala durante 2014 y 2015 Characterization of carbapenemases in Enterobacteriaceae of samples of patients who attended the San Juan de Dios General Hospital in Guatemala City during 2014 and 201
En salud pública a nivel mundial, la producción de carbapenemasas es actualmente el mayor problema de resistencia antimicrobiana. El objetivo de este estudio fue caracterizar las carbapenemasas en enterobacterias en paci...
Evaluación de una clave taxonómica, para la identificación de los géneros de helechos (Monilophyta), en Guatemala Evaluation of a taxonomic key, for the identification of fern genera (Monilophyta), in Guatemala.
El desarrollo de las tecnologías de la información y la comunicación han llevado a un cambio en la manera en que se realizan las actividades de diferentes disciplinas, incluso de las más tradicionalistas, como la taxonom...
Thrombocytopenia versus SOFA to predict mortality in patients with sepsis in the Intensive Care Unit of a tertiary hospital in Guatemala
The most common coagulation disorder in the intensive care unit is thrombocytopenia. Considering the fundamental role of platelets in hemostasis and as markers of disseminated intravascular coagulation, a significant dec...