Thrombosis Associated with Protein S Deficiency: A Case Report and Literature Review
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 10
Abstract
We have reported a rare case of deep vein thrombosis (DVT) of both legs due to protein S (PS) deficiency in a 28-year-old female. She was admitted to intensive care unit (ICU) on the basis of lower limb swelling due to thrombosis as confirmed by Doppler ultrasonography. Immunoassay by ELISA demonstrated markedly reduced total PS levels in her serum, which is likely due to a defect in the PROS1 gene. The patient was successfully treated with heparin and warfarin. This case adds to the growing evidence that PS deficiency is one of the rare cause of DVT, and also raises awareness about prophylactic treatment especially in those with PROS1 gene abnormalities or other risk factors
Authors and Affiliations
Adnan Bashir Bhatti
Keywords
Related Articles
- EP ID EP209581
- DOI -
- Views 46
- Downloads 0
Influence of Acute Back Muscle Fatigue on Repositioning Accuracy of the Knee Joint In healthy subjects
Background: The proprioceptive system is responsible for the body coordination and stability; it is a major component of function and performance in the functional activity. Purpose: To investigate the effect of acute ba...
Study on Electrophysiological Changes of Peripheral Nerves in Type 2 Diabetes Mellitus
Diabetic peripheral neuropathy is a common and disabling complication of diabetic mellitus. In diabetic neuropathy sensory, motor and autonomic functions are affected in varying degrees with sensory function predominatin...
Study of Impact of Interdisciplinary Seminar as an Integrated Teaching - Learning Innovation in M.B.B.S Students
Introduction- Integration of teaching method is very important in overcoming the barriers of learning. In order to improve learning and understanding of students, innovative educational approaches have been introduced, s...
Spontaneous Rupture of Papillary Renal Cell Carcinoma: A Rare Presentation
A 38 year-old hypertensive male patient presented with left flank swelling and pain of 2 days duration. Evaluation of the patient revealed a large left renal subcapsular hematoma with poorly functioning left kidney. Left...
Clinical study of Incisional Hernia
Incisional hernia is considered as one of the most common complication after an abdominal surgery postoperatively and an important source of morbidity. This study analyses the various modes of presentation, etiopathogene...