Thyroid pathology in patients with acromegaly: review of literature and own researches

Abstract

The analysis of medical scientific literature and retrospective analysis were performed using medical documents of patients treated in the cliniс of the State Institution “V.P. Komisarenko Institute of Endocrinology and Metabolism of the NAMS of Ukraine”, in order to study a thyroid pathology in acromegalic patients. In accordance with data of international studies, the multinodular goiter constitutes the biggest part in the structure of thyroid pathology of acromegalic patients, and the incidence of thyroid cancer ranges from 3 to 12.5 %. Among acromegalic patients who were treated in this clinic, the thyroid pathology was observed in 97.7 % of patients, and the part of multinodular goiter made up 51.2 %, autoimmune thyroiditis — 13.9 %, thyroid cancer — 4.6 %. It may be concluded that it is necessary to evaluate on a constant basis the condition of thyroid gland in acromegalic patients for timely diagnosis and treatment, especially in terms of thyroid cancer risk.

Authors and Affiliations

Yu. V. Buldygina, H. M. Terekhova, M. Yu. Bolgov, T. V. Fedko

Keywords

Related Articles

Influence of VEGFA gene polymorphisms rs2010963 and rs699947 on clinical and laboratory indicators in diabetic retinopathy among patients with type 2 diabetes mellitus

Background. A key factor of neoangiogenesis deve­lopment in diabetic retinopathy (DR) among patients with type 2 diabetes mellitus (DM) is vascular endothelial growth factor A (VEGFA). The important role of genetic polym...

Endothelial Dysfunction and Its Correction in Patients with Essential Hypertension and Type 2 Diabetes Mellitus

The article provides the results of studying the effectiveness of α-lipoic acid impact as a part of complex therapy on endothelial dysfunction in patients with essential hypertension and type 2 diabetes mellitus. There w...

Preventive diabetology at the turn of the centuries. Prevention of type 2 diabetes mellitus: achievements and prospects

This article presents the key achievements in the field of diabetes mellitus prevention. Currently, various researches have been conducted on the prevention of diabetes mellitus, with different designs, types of interven...

Morbidity and prevalence of malignant neoplasms of the thyroid gland in Ukraine and Kyiv region after the Chernobyl Nuclear Power Plant accident

Background. The annual increase in the number of newly diagnosed cases of malignant neoplasms of the thyroid gland (MNTG) is observed both in the territories most contaminated with radioiodine after the Chernobyl acciden...

Peculiarities of Hormonal Regulation of Blood Antioxidant Activity in Neuroendocrine Obesity at Different Stages of Sexual Maturation

The study is designed to establish the relationship between the rate of the induced blood lipid peroxidation and production of some hormones in adolescents. The investigations have not shown any significant alteration in...

Download PDF file
  • EP ID EP213070
  • DOI 10.22141/2224-0721.13.4.2017.106655
  • Views 99
  • Downloads 0

How To Cite

Yu. V. Buldygina, H. M. Terekhova, M. Yu. Bolgov, T. V. Fedko (2017). Thyroid pathology in patients with acromegaly: review of literature and own researches. Міжнародний ендокринологічний журнал, 13(4), 267-270. https://europub.co.uk/articles/-A-213070