Thyroid Profile in Patients with Metabolic Syndrome
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
Background: Metabolic syndrome (MS) is a cluster of metabolic abnormalities. MS and hypothyroidism are associated with increased risk of atherosclerotic heart disease. Insulin resistance is the central pathophysiological phenomenon underlying the clustering. Aims and Objective: To study the association, prevalence and types of thyroid dysfunction in patients with MS Materials and Methods: A Non-randomized Cross sectional study was done at Institute of Internal Medicine, Madras medical college and Rajiv Gandhi government general hospital, Chennai from January 2018 to April 2018. A total 0f 60 patients with MS selected according to WHO criteria were studied .Patients were evaluated based on anthropometry, evaluation of vital parameters, fasting blood sugar, lipid and thyroid profile. Statistical analysis were done using SPSS software 22.0 Results: Among 60 patients there were 45% males and 55% females. The thyroid dysfunction is 16.7% prevalent in MS, of which Subclinical hypothyroidism (SCH) was more prevalent (11.7%) compared to overt hypothyroidism (3.3%) and subclinical hyperthyroidism (1.7%). Conclusion: There was a significant prevalence of thyroid dysfunction in MS. Hence Thyroid function test (TFT) must be done in all patients with MS to assess thyroid function.
Authors and Affiliations
Dr. M. Shivanathan, Dr. K. S. Chenthil MD
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