Time-Resolved Contrast-Enhanced Magnetic Resonance Angiography Versus Digital Subtraction Angiography in Internal Carotid Artery Stenosis
Journal Title: JOURNAL OF CONTEMPORARY MEDICINE - Year 2017, Vol 7, Issue 3
Abstract
Objectives: In this study, digital subtraction angiography (DSA) being taken as a reference, the sensitivity, specificity, positive and negative predictive values (PPV and NPV), and diagnostic accuracy of time-resolved imaging of contrast kinetics magnetic resonance angiography (TRICKS MRA) was used in the detection of ICA stenosis in patients with stroke and cerebrovascular disease symptoms.Materials and methods: From April 2009 to November 2010, 22 (16 male, 6 female) consecutive patients were included in this study. MRA was performed 1.5 Tesla MR. Results of TRICKS MRA, and DSA were read independently by two observers. ICA stenosis was measured according to the following North American Symptomatic Carotid Endarterectomy Trial (NASCET) method. From the MR angiographic maximum intensity projections (MIP), the percentage of ICA stenosis was assessed on sagittal projection, which coincided with the lateral of the DSA projections used.Results: All segments throughout in 44 ICA’s compared at 56 point of stenosis in TRICKS MRA and DSA. The k statistics that reflected the interobserver variability between observers 1 and 2 were very good and similar for two tests: 0.73 for TRICKS MRA, and 0.83 for DSA. In the 70-99% carotid artery stenosis range, according to first and second independent observation, TRICKS MRA has a sensitivity of 100% and 100%; specificity of 92.3% and 94.2%; PPV of 50% and 50%, NPV of 100% and 100%, respectively, compared to digital subtraction angiography.Conclusion: TRICKS MRA which has high rates of diagnostic accuracy on determining ICA stenoses could be considered as an alternative for invasive DSA which has higher risk of complications.
Authors and Affiliations
Erkan Gökçe
Keywords
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- EP ID EP423321
- DOI 10.16899/gopctd.349805
- Views 114
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