To Evaluate Dry Eye Parameters in Patients of Primary Open Angle Glaucoma
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
Background: Open angle glaucoma and dry eye are two different pathologies exhibiting diverse ocular signs and symptoms but both have chronic progressive course requiring lifelong management. Some factors involved in pathogenesis of glaucoma such as change in level of proinflammatory cytokines in tear fluid and serum of patients with glaucoma and role of IL1 and IL6, oxidative processes and immunological mechanisms are being implicated in dry eye also. Hence this study was initiated to further explore similarities in pathogenesis of POAG and Dry Eye Disease. Aim : To evaluate dry eye parameters in cases of primary open angle glaucoma and compare the incidence of dry eye in newly diagnosed cases of POAG and already diagnosed cases of POAG instilling ocular hypotensives. Material and Methods : 150 patients were divided in 3 groups. 1st group included 50 newly diagnosed patients not instilling any antiglaucoma medication. 2nd group included 50 patients of POAG instilling ocular hypotensives. 3rd group included 50 non glaucomatous control patients. Results: Dry eye disease was found in 37 (74%) patients of newly diagnosed POAG who were not on antiglaucoma medication and 41 (81%) cases of POAG on antiglaucoma medication. Conclusion: Dry eye is pre existent in patients of glaucoma which gets exacerbated on using antiglaucoma medication. Therefore one should be careful while prescribing ocular hypotensives in cases of glaucoma as they already suffer from dry eyes.
Authors and Affiliations
Narinder Pal Singh, Surbi Taneja
Keywords
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- EP ID EP376559
- DOI 10.9790/0853-1706084247.
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