To Evaluate Dry Eye Parameters in Patients of Primary Open Angle Glaucoma
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
Background: Open angle glaucoma and dry eye are two different pathologies exhibiting diverse ocular signs and symptoms but both have chronic progressive course requiring lifelong management. Some factors involved in pathogenesis of glaucoma such as change in level of proinflammatory cytokines in tear fluid and serum of patients with glaucoma and role of IL1 and IL6, oxidative processes and immunological mechanisms are being implicated in dry eye also. Hence this study was initiated to further explore similarities in pathogenesis of POAG and Dry Eye Disease. Aim : To evaluate dry eye parameters in cases of primary open angle glaucoma and compare the incidence of dry eye in newly diagnosed cases of POAG and already diagnosed cases of POAG instilling ocular hypotensives. Material and Methods : 150 patients were divided in 3 groups. 1st group included 50 newly diagnosed patients not instilling any antiglaucoma medication. 2nd group included 50 patients of POAG instilling ocular hypotensives. 3rd group included 50 non glaucomatous control patients. Results: Dry eye disease was found in 37 (74%) patients of newly diagnosed POAG who were not on antiglaucoma medication and 41 (81%) cases of POAG on antiglaucoma medication. Conclusion: Dry eye is pre existent in patients of glaucoma which gets exacerbated on using antiglaucoma medication. Therefore one should be careful while prescribing ocular hypotensives in cases of glaucoma as they already suffer from dry eyes.
Authors and Affiliations
Narinder Pal Singh, Surbi Taneja
Keywords
Related Articles
- EP ID EP376559
- DOI 10.9790/0853-1706084247.
- Views 73
- Downloads 0
Is the ratio of pseudocholineaterase levels in pleural fluid to serum a new parameter
Background and objectives: Pleural effusion is a common clinical condition faced in everyday practice. The first step in the management of pleural effusion is its differentiation into transudates and exudates. Light’s cr...
Lipid Profile In Thalassemia Patients Common In Eastern India And It’s Correlation With Erythroid Bone Marrow Activity
Introduction Lipid abnormalities, including low levels of all fractions of serum lipids have been repeatedly reported in all phenotypes of Beta- thalassemia patients. In the present study, the low lipid profile of variou...
Sublingual Misoprostol 400 Mcg Versus Intramuscular Oxytocin 10 Iu For Prevention Of Primary Post Partum Haemorrhage: An Open-Label Randomized Clinical Trial
Introduction: Postpartum hemorrhage mostly due to uterine atony is responsible for about a third of maternal deaths. The present study is an attempt to compare the efficacy of i.v oxytocin and sublingual misoprostol for...
Is Double Consent For Abdominal Myomectomy Still Necessary?
Background: Myomectomy is one of the most frequently performed Gynaecological surgeries worldwide among gynaecologist with attendant risk of complications including conversion to hysterectomy Aim &Objective: The study ai...
Immunoglobulin G4-Related Orbital Disease With Asymmetrical Orbital Infiltration In A 65 Years Old Male – A Case Report.
Immunoglobulin G4-related disease is a systemic disease in which there is infiltration of multiple organ tissues by IgG4+ plasma cells resulting fibro-inflammatory lesion. In the region ofthehead, the disease affects the...