TO FIND OUT THE CORRELATION OF THROMBOCYTOPENIA WITH D-DIMER AN INDICATOR OF SEVERITY OF DENGUE HEMORRHAGIC FEVER
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2017, Vol 4, Issue 10
Abstract
Dengue is a mosquito-borne infectious disease, rising health problem worldwide and there is a need to find out a marker associated with severity of disease. Study was therefore designed to find out the correlation of thrombocytopenia with D-Dimer an Indicator of severity of dengue hemorrhagic fever. The study included 81 confirmed patients of dengue hemorrhagic fever, more than 18 years old who agreed to participate in study and fulfill inclusion criteria i.e. blood culture negative and IgM or NS-1 positive. The DHF patients divided in four grades according to WHO criteria. These were 55 males and 26 females. Values of platelet counts and D-Dimer were estimated. There were 53 (65.4%) cases belong to DHF-I, 20 (24.6%) cases belong to DHF-II, and 8 (9.88%) cases belong to DHF-III, and DHF-IV. 55 (67.9%) were male and 26(32.1%) were female. It is observed that 42% patients have an age of ≤ 30, 28.4% with age range 31-45 years, 29.6% with age range 46-60 years. Majority of patients (29.6%) had their platelet counts below 25000, 23.5% between 25000 and 50000. A dominant majority (72.8%) had their D dimer levels in between 201–700. Positive significant correlation (P<0.001) was observed between platelet count and D-dimer with r value 0.53. The DHF-I group had D dimer levels for all of the cases below 700. Study concluded that increased level of D-Dimer Levels along with thrombocytopenia may be an indicator of severity of dengue hemorrhagic fever.
Authors and Affiliations
Dr. Rukhshan Khurshid
Keywords
Related Articles
- EP ID EP629093
- DOI -
- Views 129
- Downloads 0
TOTAL ANTIOXIDANT CAPACITY OF LEAF, STEM, ROOT AND FLOWER OF DATURA METEL
In Srilanka it Datura metel is used in Ayurveda and Siddha treatment systems for treating bronchial asthma and chronic wound healing respectively. It is also used to maintain heath as a rejuvenating herb. The purpose of...
CUTANEOUS MANIFESTATIONS IN HIV INFECTION: A CLINICOPATHOLOGICAL STUDY
The first case of Acquired Immunodeficiency Syndrome (AIDS) was reported in Africa. But today India is considered as a new hotbed for this disease. AIDS is caused by a retrovirus human immunodeficiency virus (HIV). Two t...
SYNTHESIS OF NEW SPIRO[AZETIDINE-2,3ʹ-INDOLINE]-2ʹ,4-DIONES AS POSSIBLE ANTICANCER AGENTS: IN VITRO AND IN SILICO STUDIES
The paper describes the synthesis, and in vitro and in silico biological evaluation of twelve new spiro[azetidine- 2,3ʹ-indoline]-2ʹ,4-diones as possible anti-cancer agents. A series of six compounds have been synthesize...
KNOWLEDGE OF AWARENESS AND PRACTICE ON INJECTION SAFETY AMONG HEALTHCARE WORKERS IN YANAGOA, BEYELSA
Unsafe infection practices have inherent risk of spreading primary blood bone infection. The risk of acquiring HIV, HbsAg, and HCV infections are high among healthcare workers, therefore a need to asses and promote safe...
THE SUPPLEMENTATION OF CREATINE, MALTODEXTRIN AND LACTATE PRODUCTION DURING SPORT
The aim of this study was to examine the metabolism of lactate. During high intensity exercise, the largest tract of ATP supply are the breakdown of creatine phosphate and degradation of muscle glycogen to lactic acid. T...