To study an alteration in biochemical parameters in acute and chronic phase of respiratory acidosis and alkalosis
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2016, Vol 3, Issue 3
Abstract
Introduction: The primary abnormality in respiratory acidosis is retention of CO2 (increased H2CO3) due to impaired alveolar ventilation resulting in a rise in pCO2 causing acidemia. However, respiratory alkalosis occurs when there is decrease in H2CO3 concentration. A fall in pCO2, reduces the ratio of carbonic acid to bicarbonate resulting in alkalemia. Aim: To study variations in biochemical parameters in respect to respiratory acidosis and alkalosis. Material and Methods: The biochemical parameters of respiratory acidosis and alkalosis like blood pH, concentration of CO2, pO2, pCO2, level of HCO3 Results: The studied components of respiratory acidosis and alkalosis were found to be highly significant in chronic conditions of respiratory acidosis and alkalosis (p<0.01) than acute condition of respiratory failure when compared with the healthy controls. Conclusion: In this study, we observed that there is marked increase in product of metabolism in acute and chronic phase of respiratory syndrome when compared with the healthy controls.
Authors and Affiliations
Anita M Raut, D. V. Andure, Dilip Mhaisekar, Smita Mhaisekar, R. K. Padalkar
Keywords
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