To Study and Evaluate the Incidence o f Cutaneous Adverse Drug Reaction (CADRS ) in t he Patients At tending Dermatology Department o f A Tertiary Care Teaching Hospital
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 7
Abstract
Adverse cutaneous drug reactions (CADRs) are commonly reported type of ADRs and are caused by a wide varieties of drugs. The clinical patterns of adverse cutaneous drug reactions and the drug responsible for them is changing every years due to the emergence of newer molecules and changing trends in the use of drugs. Our objective was to evaluate the clinical pattern of CADRs and their causative drugs in the tertiary health care. It was cross sectional observational study of 1 year duration. There wre 52 patients with adverse cutaneous drug reaction were recruited. The majority of CADRs was in the age group of 18 - 35 years (63.46%). The male to female ratio was 0.79:1. Fixed drug e ruption (FDE) was the most common adverse cutaneous drug reaction (34.61%) followed by maculopapular rash (23.07%), acneform eruption (11.53%), SJS/TEN (11.53%), erythema multiforme (7.69%), urticaria (7.69%) and the most common cause was NSAIDs followe d by antimicrobial agents. Knowledge of these drug eruptions, the causative drugs are essential for the clinicians and implementing the ADRs reporting and monitoring system, one can promote drug safety and better patients care, among health care profession als.
Authors and Affiliations
Mohd Shadab
Keywords
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