To study biochemical markers in chronic obstructive pulmonary disease patients
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 4
Abstract
Introduction Chronic obstructive pulmonary disease COPD which includes chronic bronchitis and emphysema is considered as a progressive type of respiratory tract disease and is characterized by structural changes such as emphysema airflow limitation dynamic hyperinflation air trapping and peribronchial fibrotic remodeling of the lungs with significant systemic inflammatory components induced by chronic exposures to smoking andor occupational or environmental sourcesMaterials and Methods This case control study was conducted on 60 subjects in which 30 were healthy controls and 30 were cases of COPD Patients with history of respiratory disease other than COPD cardiac diseases and neuromuscular disease were excluded 30 healthy age and gender matched nonsmoker adults were selected as control groupResults Unpaired t test was performed and it was observed that Total Cholesterol Triglyceride Low Density Lipoprotein Lactate dehydrogenase levels were significantly higher and serum concentrations of High Density Lipoprotein was decreased significantly in cases as compared to controlsConclusion Serum LDH levels are altered in many respiratory diseases but it has not been studied in depth in COPD patients In view of this we conducted the study and our results shows that patients with COPD have raised serum LDH levelsKeywords Smoking COPD Lactate dehydrogenase
Authors and Affiliations
Niranjan Singh, Sandeep Kumar Sharma, K V. Thimmaraju, Mona Tilak
Keywords
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- EP ID EP475447
- DOI 10.18231/2394-6377.2018.0133
- Views 72
- Downloads 0
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