To Study the Association and Significance of Hyponatremia in Pneumonia in Paediatric Patients Treated in Hospital Setting
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 1
Abstract
Introduction: Hyponatremia commonly occur in pneumonia patients on admission and they are known to have worse outcome. Current study was done to see the association and significance of hyponatremia in relation to severity and final outcome in pneumonia cases. Material and methods: Current prospective observational study was conducted in patients admitted in paediatric wards of a tertiary care hospital. Study was done in 100 children of 1 month-5 years of age of both sexes having pneumonia. Serum sodium concentration was measured on admission and at 24 and 48 hours in children hospitalised for pneumonia, diagnosed clinically and radiologically. Some other blood investigations were done and clinical outcome e.g- complications, recovery and death were noted. Hyponatremic and normonatremic groups were to be compared for all outcomes by- student-t test or Fischer-exact test as applicable. Results: Community Acquired Hyponatremia (CAH) [serum sodium < 135 mEq/L at 0 hour] was present in 21 cases (21%) e.g- hyponatremic group (HN) and rest 79 cases (79%) were in normonatremic group (NN). Hyponatremia was mostly mild. On admission, patients in HN group had higher - body temperature, longer tachypnoea, time for defervescence, hospital stay and longer oxygen requirement. Hyponatremic patients also showed higher CRP level, WBC Count and Neutrophil proportion. Death was 19.25 times likely in HN group. All the moderate and severe hyponatremia cases were expired and showed a statistically significant correlation between hyponatremia and worse outcome in pneumonia. Hospital- aggravated hyponatremia had a correlation with increased morbidity but not with mortality and hospitalacquired hyponatremia showed no such correlations. Conclusion: Hyponatremia is common in pneumonia and it is a strong indicator of higher morbidity in children hospitalized for pneumonia.
Authors and Affiliations
Partha Pratim Mandal, Madhu Garg, I. P. Choudhary
Keywords
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