To Study the Biochemical Aspect and Dependence in Alcoholic Liver Disease (ALD)
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 2
Abstract
Background: Geographical variations exists regarding intake of alcohol, highest burden of alcohol-related disease is in developed world with subgroups who drinks excessively or are alcohol abusers and problem. Studies have shown that dependence severity is associated with young age and family drinking history with early neural attention biases to alcohol cues. The definitive diagnosis of any form of alcohol-related hepatic disorders needs to take evidence of alcohol consumption into account hence this study was designed, to study the biochemical aspects and dependence in alcoholic liver disease. Methodology: This prospective, cross sectional study was conducted in patients suffering from Alcoholic Liver Disease. Patients who fulfilled the inclusion and exclusion criteria were enrolled in the study if they are willing to give written informed consent. The patients were also subjected to Severity of Alcohol Dependence Questionnaire (SADQ). Results: A total of 30 patients were enrolled in the study, 17 patients were suffering from cirrhosis and 13 patients had fatty liver. The mean SDAQ score was 23.83±2.6 suggesting moderate dependence as per SADQ scores. The patients with fatty liver had lower levels of various biochemical tests but it was not statistically significant. Patients with fatty liver also had a higher SADQ scores but it was not statistically significant. There was no statistically significant correlation with the various biochemical parameters. Conclusions: To conclude our study demonstrated that patients with manifestation of fatty liver and cirrhosis had moderate dependence on alcohol, and this was more in patients with fatty liver.
Authors and Affiliations
Ajitpal Singh Gill, Guramrit Kaur Gill
Keywords
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- EP ID EP540254
- DOI 10.21276/ijmrp.2018.4.2.081
- Views 59
- Downloads 0
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