To Study the Effect of Pre-Emptive Dose of Pregabalin for Postoperative Analgesia in Patients Undergoing Surgery under General Anaesthesia
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 11
Abstract
Abstract: Successful recovery after surgery depends on complication free postoperative period. Pre-emptive use of analgesic agents reduces total analgesic consumption after surgery and increases patients comfort. Our hypothesis is that pre-emptively given oral pregabalin reduces postoperative pain in patients scheduled for surgery under general anaesthesia. This randomized control study was conducted on 60 patients of ASA grade 1 and 2 after taking ethics committee approval. Patients were divided into two groups. In Group P (n=30), patients who received 300 mg of Pregabalin orally one and half hours prior to surgery and in group C, patients received Placebo orally one and half hours prior to surgery. Diastolic, systolic and mean blood pressure, heart rate were measured throughout the procedure. Time of rescue analgesia and VAS score was recorded postoperatively. oral pregabalin given pre-emptively provides postoperative analgesia. Mean duration of first rescue analgesia in group P was that was 58.69±25.21 in comparison to group C 38.40±24.61. Time of second rescue analgesia in group P was 132.06±23.77 and in group C was 100.86±30.26 showing better analgesia in group P when compared with group C (p<0.05). oral pregebalin given pre-emptively reduces postoperative pain in patients scheduled for surgery under general anaesthesia.
Authors and Affiliations
Anju Gautam, Nidhi Sharma, Ritu Masar, Neelima Tandon
Keywords
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