TO STUDY THE ROLE OF ECHOCARDIOGRAPHY IN DETECTING VARIOUS CARDIAC CHANGES IN CHRONIC KIDNEY DISEASE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 24
Abstract
BACKGROUND Chronic kidney disease (CKD) is a major public health problem worldwide with increasing incidence and prevalence. Diabetes and hypertension are the leading cause of CKD worldwide, whereas hypertension is a cause as well as effect of CKD. Aim- To compare the cardiac function in hypertensive and normotensive CKD patients with normal subjects. MATERIALS AND METHODS This is a descriptive comparative study. End stage renal disease (ESRD) patients who were at stage III - V and on maintenance dialysis were subjected to 2D echo for determining various cardiac changes during the period of 1st January 2014 to 31st December 2014 in the Department of Medicine of GSVM Medical College, Kanpur and were included in the study. Patients with clinical evidence of coronary artery diseases, valvular heart disease, congenital heart disease and pericardial effusion were excluded from the study. RESULTS Out of 42 ESRD patients, 72% showed diastolic dysfunction, 60% showed left ventricular hypertrophy and global wall hypokinesis in 52%. Other echocardiography findings were pericardial effusion in 36% and LA is enlarged in 36%. Clinically, there was no valvular involvement, but by echocardiography, mitral regurgitation was most commonly involved (p < 0.01). Next were tricuspid valve (p < 0.01) and aortic valve was common (36%). There were no severe regurgitant lesions and involvement of pulmonary valve. CONCLUSION Cardiac structural as well as functional abnormalities are common in patients of CKD, more in hypertensive than in normotensive patients. Diastolic dysfunction is the commonest cardiac abnormality followed by LVH. Echocardiography is cost effective and is a non-invasive diagnostic test for asymptomatic CKD patients, especially in hypertensives. This is important for early preventive measures and to check progress of the disease.
Authors and Affiliations
Prem Singh, Reena Singh, Rajeev Gupta, Gautam S. K. , Brijesh Kumar
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