Topical heparin for infusion associated superficial thrombophlebitis : A preventive approach
Journal Title: Journal of the Indian Medical Association - Year 2018, Vol 116, Issue 12
Abstract
Maintaining a single indwelling intravenour (IV) catheter for a long duration is limited mainly due to the development of superficial thrombophlebitis. This, we decided to evaluate the efficacy and safety of heparin sodium topical solution (1000 IU/ml) in preventing infusion associated superficial thrombophlebitis. An open label, single arm clinical study was conducted. Patients undergoing elective surgery and planned to remain in situ with intravenous cannulation for at least 48 hours indoor, period were screened for the eligibility. In 47 enrolled patients were cannulated on back of the hand with IV cannula no 18. Treatment with 6 to 8 drops of Heparin Sodium Topical Solution (1000 IU/ml) was initiated immediately after the cannulation and baseline reading followed by reading every 8 hours for the treatment period of 48 hours (total 7 doses) was recorded. Patients were observed for sign and sympotoms of phlebitis developed and Graded as per Visual Infusion Phlebitis Scale. None of the patients progressed to Grade II from baseline phlebitis Grade during the study period and no application site reaction was observed in the patients. A trend towards pervention of infusion related superficial thrombophlebiotis was observed with heparin sodium topical solution (100 IU/ml).
Authors and Affiliations
Rajat Charan, Tushar Chaurasia
Keywords
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