Topical ophthalmic in situ gels for ocular delivery: A recent Update
Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2017, Vol 3, Issue 7
Abstract
Abstract: Ocular drug delivery is challenging field to pharmaceutical scientists owing to the underlying anatomical, physiological and dynamic constraints put forth by the eye. Nonetheless, there is increasing need to overcome these barriers for the treatment of sight threatening ophthalmic ailments. Novel drug delivery strategies are being explored while intravitreal injections are still a standard treatment for the efficient treatment of ocular disorders. Topical ophthalmic in situ gels could be viable platform to increase mucoadhesivity, pre-corneal residence and thereby ocular bioavailability of drugs. In this review, various topical in situ gel formulations exploited for ocular delivery are summarized. Keywords: Ocular delivery, topical in situ gels, ocular absorption and bioavailability, retinal delivery, ocular pharmacokinetics.
Authors and Affiliations
Anil Kumar G, Rama rao A, Thirupathi G, Ramesh B
Keywords
Related Articles
- EP ID EP391755
- DOI -
- Views 80
- Downloads 0
Pattern of Blood Pressure Distribution Among Members of Staff in AdekunleAjasin University AkungbaAkoko, Ondo State, Nigeria
Abstract: This study was designed to find out the pattern of blood pressure distribution among members of staff in AdekunleAjasin University AkungbaAkoko (AAUA), Ondo State, Nigeria. A cross sectional descriptive survey...
Recognition System of Herbal Medicine on Mobile Terminal Based on Android Platform
Abstract: In order to recognize the Chinese herbal medicine our side and to provide the help for the Chinese herbal medicine lovers, we design a kind of recognition system of herbal medicine by our mobile terminal based...
Prospective Study of Sevoflurane with Laryngeal Mask Airway in Children
The aim of the study was to study effectiveness of inhalation sevoflurane with the laryngeal mask airway (LMA) in children undergoing surgeries below umbilicus. Thirty premedicated children 3-12 years old with the Americ...
Relationship of Workload and Working Conditions to Stress Level of Nurse in Intensive Care Unit (ICU)(Pandan Hospital, Tapanuli Tengah, 2017)
Abstract:Stress is a stimulus or a stressful situation. If the situation is a stressful job situation, then stress on work can be caused by several factors, including workload and working conditions. The ICU nurse must m...
Contraceptive Prevalence amongst Married Women in Bayelsa State, Nigeria
Abstract: A study on the contraceptive prevalence amongst married women residing in Bayelsa State was carried out. Its principal objectives was to carry out a random estimate of contraceptive prevalence amongst married w...