Toxic epidermal necrolysis: an update
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2013, Vol 3, Issue 2
Abstract
Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a rare, life-threatening dermatological condition that is usually induced by reaction to medications. It is characterized by the detachment of the top layer of skin (the epidermis) from the lower layers of the skin (the dermis) all over the body. There is broad agreement in medical literature that TEN can be considered a more severe form of Stevens Johnson syndrome, and debate whether it falls on a spectrum of disease that includes erythema multiforme. Some authors consider that there is an overlap between the two syndromes (usually between 10% and 30% of skin detachment). This article deals with history, epidemiology, diagnosis, pathophysiology treatment and management of TEN.
Authors and Affiliations
Keywords
Related Articles
- EP ID EP231119
- DOI 10.1016/S2222-1808(13)60051-1
- Views 56
- Downloads 0
reliminary phytochemical screening and in vitro antibacterial activity of Bauhinia variegata Linn. against human pathogens
Objective: To investigate the antimicrobial and phytochemical properties of hydromethanolic extracts of Bauhinia variegata Linn. (B. variegata) (leaf, stem bark and flower) to justify the traditional claim endowed upon t...
SEVA TB ELISA - Multi antigen and antibody assays for serodiagnosis of suspected cases of pulmonary and extra pulmonary tuberculosis in tertiary care hospital -A retrospective study
Objective: To assess the usefulness of in-house developed multiantigen and antibody assays, in diagnosis of both pulmonary and extra-pulmonary tuberculosis. Method: Clinically suspected cases of 31 pulmonary and 171 extr...
Efficacy of essential oils of aromatic plants as larvicide for the management of filarial vector Culex quinquefasciatus Say (Diptera: Culicidae) with special reference to Foeniculum vulgare
Objective: To evaluate the larvicidal activity of essential oils derived from ten aromatic plants with special reference to Foeniculum vulgare (F. vulgare) against early fourth instar larvae of Culex quinquefasciatus (Cx...
Early diagnosis in an unusual presentation of tubercular pericarditis-A case report
Patients with tuberculosis sometimes may present with atypical, unusual features. The reported case is of 57 years male admitted with chief complaint of fever and breathlessness. Spiral CT chest revealed significant peri...
Developing ultra deformable vesicular transportation of a bioactive alkaloid in pursuit of vitiligo therapy
Objective: To develop transfersomal formulation integrated with piperine intended for vitiligo. Methods: Film hydration technique was employed in the preparation of transfersomes. Modified diffusion cell, consistency tes...