Traditional Chinese medicine treatment of immune-related pneumonia caused by PD-1/PD-L1 inhibitors
Journal Title: TMR Clinical Research - Year 2020, Vol 3, Issue 2
Abstract
With the wide application of immunotherapy drug PD-1/PD-L1 inhibitor in China and the continuous clinical research, a major problem that we have to face is the immune-related pneumonia caused by PD-1/PD-L1. At present, western medicine mainly treated it by hormone therapy, which may cause side effects, such as obesity, osteoporosis and osteonecrosis for hormone therapy by long-term, and increase the patients' pain. Under the guidance of the theory of syndrome differentiation, traditional Chinese medicine (TCM) advocates the methods of expelling wind and clearing away cold, resolving phlegm and relieving asthma, relieving heat from lung, and invigorating the spleen and tonifying the kidney, etc. Exact differentiation of symptoms and rational usage of drugs can play an important role in the early prevention and treatment of immune-related pneumonia, reflecting the important role of TCM in the prevention and treatment of side effects of new drugs. In order to provide an effective clinical reference for clinicians in the practice of using PD-1/PD-L1, this paper systematically reviewed the use of TCM in the treatment of immune-related pneumonia induced by PD-1/PD-L1 inhibitors.
Authors and Affiliations
Xun Sun, Bing Dai, Liang Lei
Keywords
Related Articles
- EP ID EP683401
- DOI 10.12032/TMRCR20200419006
- Views 179
- Downloads 0
Construction of an intelligent patient satisfaction assessment system and its application in emergency management
Hospital emergency management work is of great importance which not only related to the life and health of the people but also related to social stability. It is necessary to construct and improve the patient satisfacti...
Relationship between cognitive level of ethical atmosphere for psychiatric nurses and attitude of discriminating against mental patients
Objective: To explore the relationship between mental nurses' discrimination against mental patients and the cognitive level of ethical atmosphere. Methods: Convenience sampling was adopted, 147 psychiatric nurses from...
Diagnostic value and clinical significance of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio combined with carbohydrate antigen in endometrial carcinoma
Background: To explore diagnostic value and clinical significance of preoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) combined with serum carbohydrate antigen (CA), including CA12...
Acute uterine inversion at cesarean section: an emergency condition in obstetrics
A 18-year-old local Han Chinese primigravida woman suffered with severe pre-eclampsia. After blood pressure stabilization, convulsion prophylaxis and fetal lung maturity enhancement, emergency cesarean section was perfor...
Evaluation of autophagy-related genes and lncRNAs signature for prognositic prediction in thyroid carcinoma via bioinformatics analysis
Autophagy plays a significant role in the pathogenesis and prognosis of thyroid carcinoma. The role of autophagy-related genes and long non-coding RNAs, as well as the risk model of thyroid carcinoma patients were in...