Traditional Chinese medicine treatment of immune-related pneumonia caused by PD-1/PD-L1 inhibitors
Journal Title: TMR Clinical Research - Year 2020, Vol 3, Issue 2
Abstract
With the wide application of immunotherapy drug PD-1/PD-L1 inhibitor in China and the continuous clinical research, a major problem that we have to face is the immune-related pneumonia caused by PD-1/PD-L1. At present, western medicine mainly treated it by hormone therapy, which may cause side effects, such as obesity, osteoporosis and osteonecrosis for hormone therapy by long-term, and increase the patients' pain. Under the guidance of the theory of syndrome differentiation, traditional Chinese medicine (TCM) advocates the methods of expelling wind and clearing away cold, resolving phlegm and relieving asthma, relieving heat from lung, and invigorating the spleen and tonifying the kidney, etc. Exact differentiation of symptoms and rational usage of drugs can play an important role in the early prevention and treatment of immune-related pneumonia, reflecting the important role of TCM in the prevention and treatment of side effects of new drugs. In order to provide an effective clinical reference for clinicians in the practice of using PD-1/PD-L1, this paper systematically reviewed the use of TCM in the treatment of immune-related pneumonia induced by PD-1/PD-L1 inhibitors.
Authors and Affiliations
Xun Sun, Bing Dai, Liang Lei
Keywords
Related Articles
- EP ID EP683401
- DOI 10.12032/TMRCR20200419006
- Views 177
- Downloads 0
Professor Jia Chunsheng's instruction on clinical application of "elements for acupuncture effect orientation" in the Song to Elucidate Mysteries
Professor Jia Chunsheng is one of the sixth of old traditional Chinese medicine experts, and often instructs students in ordinary clinics to attach importance to learning and clinical practices of classic works. Now Prof...
Clinical observation of 36 patients with chronic nephritis proteinuria treated with Zhuangshen Gujing decoction
Objective: Our goal was to examine the impact of Zhuangshen Gujing decoction on proteinuria associated with chronic nephritis. Methods: 72 patients with chronic nephritis proteinuria were divided randomly into two groups...
Cardiac exercise rehabilitation for heart failure: a review of the literature
The most common symptom of patients with heart failure is reduced exercise tolerance, as indicated by decreased peak oxygen uptake (VO2peak), which is associated with both reduced quality of life and survival. Cardiac...
Influence of overweight in pregnancy on the intestinal flora as well as maternal and infant outcome
Currently, the influence of change in the intestinal flora on the human body has become a popular topic for clinical research. Several studies show that the nutritional balance, physiological metabolism, immune protectio...
Research on the aetiology and treatment of premature ovarian insufficiency
Premature ovarian insufficiency, as a complex gynaecological disease, seriously threatens the physical and mental health of women of childbearing age. The main reasons for its pathogenesis are summarized. As a complex gy...