Transfusion Support and Red Cell Alloimmunisation in Thalassemia Patients
Journal Title: Haematology International Journal - Year 2018, Vol 2, Issue 2
Abstract
Thalassemias are the most common mono genetic disease worldwide. It has high frequency extending from the Mediterranean basin through the Middle East (Iran), India and Southeast Asia. In India, the carrier rate of Beta Thalassemia varies from 3-17%.
Authors and Affiliations
Dibyajyoti Sahoo
Cladribine an Alternative for Midostaurine in FLT3 Positive Acute Myeloid Leukemia
Midostaurinis registered for the indication newly diagnosed acute myeloid leukemia that is FLT3 mutation positive in combination with standard cytarabine and daunorubicine induction and cytarabine consolidation. The regi...
Environmental Factors as Determinants of Severity of SCD in Nigeria
Sickle cell anaemia (SCA) is a chronic blood disorder characterized by red blood cells that assume an abnormal sickle shape when deoxygenated and may block different areas of the microcirculation causing ischaemia in var...
Management of Adult Onset Familial Hemophagocytic Lymphohistiocytosis (FHL): A Dilemma
Background: Perforin gene (PRF1) mutations cause the familial form of hemophagocytic lymphohistiocytosis (HLH). Case presentation: Here, we report a 36-year-old male with familial HLH, who was initially thought to be se...
Role of α-1 Anti Trypsin, A Constitutive Form of Nitric Oxide Synthase in Cyclic AMP Mediated Inhibition of Platelet Aggregation
1.1. Introduction: As reported before, the treatment of platelets with all currently known platelet aggregating agents was resulted in the reduction of nitric oxide (NO) synthesis through the inhibition of enzyme nitric...
Expanding the Classification of Leukemia by the World Health Organization over Time
The classification has always been the basis for many treatments of the disease. The French-American-British has performed leukemia classification base on morphological finding, but the World Health Organization apply ge...