TREATMENT OF CYANIDE POISONING IN CROSSBRED COWS: A PROFILE OF DRUG SYNERGISM
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 10
Abstract
Five cross breed cows suffering from cyanide poisoning were treated. Immaturely cut sorghum grass in pre monsoon season fed to animals was identified as a cause of poisoning. All the animals exhibited the severe clinical signs of poisoning like dyspnoea, anxiety, restlessness, staggering gait as well as tremors. All five cows were treated immediately at nearby farms where they were kept. While treating cows, three among five were administered saturated jaggery liquid prior to literature based allopathic SID treatment of 15 gm IV administration of Sodium nitrite and Sodium thiosulphate combination, where as rest two were given only allopathic treatment of Sodium nitrate and Sodium thiosulphate combination (15 gm IV). Cows which were treated with both jaggery and allopathic therapeutics recovered fast as compared to cows treated with allopathic therapeutics alone. Result suggests that jaggery play a synergistic action with allopathic therapeutics and responsible for early recovery from clinical symptoms of poisoning.
Authors and Affiliations
Harshad Patel , Shailesh Mody , Chirag Modi , Hitesh Patel , Sushant Parekar
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