Triglycerides levels in schizophrenia: A comparative study among untreated, treated and their first degree relatives
Journal Title: Medpulse International Journal of Medicine - Year 2017, Vol 4, Issue 1
Abstract
Objective: To compare any differences in the lipid profile of untreated schizophrenia patients, treated schizophrenia patients and their first degree relatives. Methodology: The Study is conducted among untreated schizophrenia patients, treated schizophrenia patients and their first degree relatives who came to Mamata general hospital, Khammam. Total study sample consists of 90 out of which there are 30 treated schizophrenic patients, 30 untreated schizophrenic patients and 30 first degree relatives of either group who were randomly selected. Estimation of Triglycerides by Enzymatic Colorimetric Test: (GPO/PAP ethod). Results: Mean triglycerides was significantly higher in treated schizophrenics compared to untreated chizophrenics and FD. There was significantly higher rate of hypertriglyceridemia in patients treated with anti-psychotics when compared to drug naive and first degree relatives. There were no significant ifferences in rate of hypertriglyceridemia between FDR and drug naive patients. Conclusion: Use of second generation antipsychotics in schizophrenia patients significantly affects lipid profile, which increase triglyceride levels abnormally.
Authors and Affiliations
B Ramakrishna, Murali Krishna V, Vijay Kumar M, Raghuram Macharapu
Keywords
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