Tumor necrosis factor alpha in smokers and non-smokers
Journal Title: Journal of Biodiversity and Environmental Sciences (JBES) - Year 2014, Vol 4, Issue 2
Abstract
Previous investigations have described a positive association between smoking and systemic inflammation. To compare serum Tumor necrosis factor alpha (TNF-α) between smoker and non-smoker men, fifteen healthy adult smoker and the same number non-smoker men matched for age and body mass index participated in this study by accessible sampling. To determine difference in serum TNF-α between two group, their blood samples were collected an overnight fast. Independent sample T-test was used to compare the serum levels of TNF-α between smoker and non smoker subjects. There was not significant difference in serum TNF-α between smoker and nonsmoker groups. These data do not support the inflammatory property of smoking. Further studies are needed to clarify possible mechanisms by which smoking affect systemic inflammation by TNF-α or other cytokines.
Authors and Affiliations
Behbudi Laleh, Sedaghati Saeid, Sokhanguei Yahya, Afsharmand Zohreh
Keywords
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