Tumors in rheumatic diseases
Journal Title: Advances in Hygiene and Experimental Medicine - Year 2013, Vol 67, Issue 0
Abstract
Patients with systemic inflammatory rheumatic diseases (such as rheumatoid arthritis, lupus erythematosus, systemic sclerosis, idiopathic inflammatory myopathies, or Sjögren’s syndrome) are at increased risk of cancer, including hematological malignancies (leukemias and lymphomas), as well as non-hematological cancers (e.g. lung, esophageal, prostate or ovarian cancer). This increased risk for cancer development in patients with rheumatic diseases is attributed to the immune (autoimmune) processes and the medical treatment. Due to the often similar symptoms and the occurrence of systemic paraneoplastic syndromes it is very important to evaluate the association between rheumatic diseases and cancer. This paper presents issues concerning the development of cancer in patients with rheumatic diseases and the risk of cancer associated with drugs used for the treatment of rheumatic diseases.
Authors and Affiliations
Jerzy Świerkot, Aleksandra Lewandowicz-Uszyńska, Katarzyna Bogunia-Kubik
Keywords
Related Articles
- EP ID EP67224
- DOI -
- Views 138
- Downloads 0
Konsekwencje pozawątrobowe zakażenia wirusem zapalenia wątroby typu C (HCV)
Wirus zapalenia wątroby typu C jest wirusem pierwotnie hepatotropowym. Jednak u pacjentów przewlekle zakażonych HCV obserwuje się liczne objawy pozawątrobowe np. krioglobulinemię, zaburzenia limfoproliferacyjne, choroby...
The physiological role of nucleobindin-2/nesfatin-1 and their potential clinical significance
Nucleobindin-2 is a multidomain protein. Nucleobindin-2 can be cleaved into three peptide products: nesfatin-1, nesfatin-2 and nesfatin-3. It has been also shown that both Nucleobindin-2 and nesfatin-1 exhibit anorexigen...
Vaccinomics and adversomics as new trends in vaccinology
Currently used vaccines have been developed based on experimental pre-clinical and clinical trials. Although the widespread availability of vaccines is one of the greatest achievements in public health, the selection of...
Odkrycie neuromedyny U i jej rola w centralnej regulacji homeostazy energetycznej
Neuromedyna U (NMU) jest neuropeptydem o wysoce konserwatywnej strukturze, a jej receptory (NMUR1 i NMUR2) należą do rodziny receptorów związanych z białkami G (GPCR) zaliczanych do grupy tzw. receptorów sierocych. Akty...
Immune disorders in sepsis and their treatment as a significant problem of modern intensive care
Despite the great advances in the treatment of sepsis over the past 20 years, sepsis remains the main cause of death in intensive care units. In the context of new possibilities of treating sepsis, a comprehensive respon...