Ultrasound Densitometry in the Diagnosis of Disorders of Bone Mineral Density in Patients with Thyroid Pathology
Journal Title: Міжнародний ендокринологічний журнал - Year 2015, Vol 6, Issue 70
Abstract
The objective of this study was to establish the relationship between the levels of thyroid hormones and characteristics of bone tissue according to radiological and laboratory methods. To assess the influence of thyroid hormone levels on the bone tissue, there was performed a comparative study of four groups of patients aged 19 to 49 years. The main study groups consisted of 34 patients with diffuse toxic goiter (DTG) and 42 patients with overt primary hypothyroidism. A comparison group included 23 patients with diffuse nontoxic goiter and preserved functional state of the thyroid gland (indicators of thyroid-stimulating hormone (TSH) and fT4 were not statistically significantly different from the control group data). The control group is presented by 20 apparently healthy persons. It was found that excessive production of thyroid hormone with a pronounced inhibition of TSH (0.08 ± 0.03 µIU/ml) in patients with DTG, as well as reduced thyroid function with higher levels of TSH (8.24 ± 3.16 µIU/ml) in patients with overt hypothyroidism, lead to disturbances in the system of bone metabolism: in thyrotoxicosis — increase with the predominance of resorption, and in hypothyroidism — decrease of bone remodeling. Ultrasonic densitometry has shown a statistically significant decrease of bone density values and increased incidence of osteopenia and osteoporosis compared to apparently healthy individuals. The development of hyperthyroidism in the age under 30 increases the risk of osteopenic syndrome in patients with DTG. The incidence of osteopenic syndrome in patients with overt hypothyroidism does not depend on age.
Authors and Affiliations
N. I. Balatska, I. V. Pankiv
Keywords
Related Articles
- EP ID EP219431
- DOI -
- Views 75
- Downloads 0
Modern Views on the Algorithm of Management of Pregnant Women and Women in Labor with Diffuse Toxic Goiter
The article presents the modern views and data on the risk factors, mechanisms of development, clinical features and complications of diffuse toxic goiter during the pregnancy, labor, in the postpartum period and in newb...
Influence of Hypoglycemic Therapy on the Body Weight Dynamics
The lecture examines the impact of treatment with different groups of hypoglycemic drugs on the body weight of patients with type 2 diabetes mellitus. The schemes for rational pharmacotherapy of patients with type 2 diab...
Autoimmune Disorders in Endocrine Pathology. A New Look on the Diagnosis and Management According to the Materials of 18th European Congress of Endocrinology (Munich, May 2016)
The paper presents the current data on the effect of the presence of autoantibodies on the management of autoimmune diseases: autoimmune thyroiditis, diabetes mellitus, states of carriage of antithyroid and diabetes-asso...
The relation of the dynamics of anthropometric data in obese women of childbearing age with treatment type
The aim was to study efficiency of pathogenetic therapy and dynamics of anthropometric indexes in obese women of childbearing age having different endocrine pathology before and 6 months later after treatment. Materials...
Brain Lesions in Patients with Type 2 Diabetes Mellitus
The objective of research — to establish the causes and patterns of structural and functional changes in the brain of patients with type 2 diabetes with ischemic stroke in order to improve the diagnosis, evaluation of th...